# IntrAgent: An LLM Agent for Content-Grounded Information Retrieval through Literature Review

arXiv: https://arxiv.org/abs/2604.22861 · HTML: https://mlsanity.com/paper/2604.22861/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Placed in Web, search, and research agents, one of 16 directions in LLM agents and tool use.
- Builds on 35 of its 87 references that are in the map.
- First posted on arXiv 23 Apr 2026.

## Placed in

- LLM agents and tool use / [Web, search, and research agents](https://mlsanity.com/agents/web-search-and-research-agents/)

## Builds on (most cited first, 30 of 35)

- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [TriviaQA: A Large Scale Distantly Supervised Challenge Dataset for Reading Comprehension](https://mlsanity.com/paper/1705.03551/) (2017)
- [GPQA: A Graduate-Level Google-Proof Q&A Benchmark](https://mlsanity.com/paper/2311.12022/) (2023)
- [Can a Suit of Armor Conduct Electricity? A New Dataset for Open Book Question Answering](https://mlsanity.com/paper/1809.02789/) (2018)
- [Learn to Explain: Multimodal Reasoning via Thought Chains for Science Question Answering](https://mlsanity.com/paper/2209.09513/) (2022)
- [MathVista: Evaluating Mathematical Reasoning of Foundation Models in Visual Contexts](https://mlsanity.com/paper/2310.02255/) (2023)
- [Know What You Don't Know: Unanswerable Questions for SQuAD](https://mlsanity.com/paper/1806.03822/) (2018)
- [MiniLM: Deep Self-Attention Distillation for Task-Agnostic Compression of Pre-Trained Transformers](https://mlsanity.com/paper/2002.10957/) (2020)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [OlympiadBench: A Challenging Benchmark for Promoting AGI with Olympiad-Level Bilingual Multimodal Scientific Problems](https://mlsanity.com/paper/2402.14008/) (2024)
- [The AI Scientist: Towards Fully Automated Open-Ended Scientific Discovery](https://mlsanity.com/paper/2408.06292/) (2024)
- [Reading Wikipedia to Answer Open-Domain Questions](https://mlsanity.com/paper/1704.00051/) (2017)
- [Crowdsourcing Multiple Choice Science Questions](https://mlsanity.com/paper/1707.06209/) (2017)
- [CoQA: A Conversational Question Answering Challenge](https://mlsanity.com/paper/1808.07042/) (2018)
- [ChemCrow: Augmenting large-language models with chemistry tools](https://mlsanity.com/paper/2304.05376/) (2023)
- [A Dataset of Information-Seeking Questions and Answers Anchored in Research Papers](https://mlsanity.com/paper/2105.03011/) (2021)
- [Agent Laboratory: Using LLM Agents as Research Assistants](https://mlsanity.com/paper/2501.04227/) (2025)
- [HybridQA: A Dataset of Multi-Hop Question Answering over Tabular and Textual Data](https://mlsanity.com/paper/2004.07347/) (2020)
- [Assisting in Writing Wikipedia-like Articles From Scratch with Large Language Models](https://mlsanity.com/paper/2402.14207/) (2024)
- [PaperQA: Retrieval-Augmented Generative Agent for Scientific Research](https://mlsanity.com/paper/2312.07559/) (2023)
- [Language agents achieve superhuman synthesis of scientific knowledge](https://mlsanity.com/paper/2409.13740/) (2024)
- [LongRAG: Enhancing Retrieval-Augmented Generation with Long-context LLMs](https://mlsanity.com/paper/2406.15319/) (2024)
- [A Comprehensive Survey of Scientific Large Language Models and Their Applications in Scientific Discovery](https://mlsanity.com/paper/2406.10833/) (2024)
- [Enhancing LLM Factual Accuracy with RAG to Counter Hallucinations: A Case Study on Domain-Specific Queries in Private Knowledge-Bases](https://mlsanity.com/paper/2403.10446/) (2024)
- [Agent Lumos: Unified and Modular Training for Open-Source Language Agents](https://mlsanity.com/paper/2311.05657/) (2023)
- [Retrieval-Augmented Generation for Natural Language Processing: A Survey](https://mlsanity.com/paper/2407.13193/) (2024)
- [LitLLM: A Toolkit for Scientific Literature Review](https://mlsanity.com/paper/2402.01788/) (2024)
- [HoneyComb: A Flexible LLM-Based Agent System for Materials Science](https://mlsanity.com/paper/2409.00135/) (2024)
- [ChemAgent: Self-updating Library in Large Language Models Improves Chemical Reasoning](https://mlsanity.com/paper/2501.06590/) (2025)

## Built on by (most cited first, 2 of 2)

- [FragFuse: Bypassing Access Control of Large Language Model Agents via Memory-Based Query Fragmentation and Fusion](https://mlsanity.com/paper/2606.15609/) (2026)
- [LinePilot Digitizer: Line-Plot Recovery with Manual and Automatic Calibration](https://mlsanity.com/paper/2609.19377/) (2026)

## Abstract (arXiv)

Scientific research relies on accurate information retrieval from literature to support analytical decisions. In this work, we introduce a new task, INformation reTRieval through literAture reVIEW (IntraView), which aims to automate fine-grained information retrieval faithfully grounded in the provided content in response to research-driven queries, and propose IntrAgent, an LLM-based agent that addresses this challenging task. In particular, IntrAgent is designed to mimic human behaviors when reading literature for information retrieval -- identifying relevant sections and then iteratively extracting key details to refine the retrieved information. It follows a two-stage pipeline: a Section Ranking stage that prioritizes relevant literature sections through structural-knowledge-enabled reasoning, and an Iterative Reading stage that continuously extracts details and synthesizes them into concise, contextually grounded answers. To support rigorous evaluation, we introduce IntraBench, a new benchmark consisting of 315 test instances built from expert-authored questions paired with literature spanning five STEM domains. Across seven backbone LLMs, IntrAgent achieves on average 13.2% higher cross-domain accuracy than state-of-the-art RAG and research-agent baselines.
