# Thinking Like a Botanist: Challenging Multimodal Language Models with Intent-Driven Chain-of-Inquiry

arXiv: https://arxiv.org/abs/2604.20983 · HTML: https://mlsanity.com/paper/2604.20983/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning.
- Builds on 8 of its 86 references that are in the map.
- First posted on arXiv 22 Apr 2026.

## Placed in

- LLM reasoning / [Clinical and biomedical applications](https://mlsanity.com/lr/clinical-and-biomedical-applications/)
- Multimodal LLMs / vision-language models / [Agricultural vision-language models](https://mlsanity.com/mllm/agricultural-vision-language-models/)

## Builds on (most cited first, 8 of 8)

- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Multimodal Chain-of-Thought Reasoning in Language Models](https://mlsanity.com/paper/2302.00923/) (2023)
- [PathVQA: 30000+ Questions for Medical Visual Question Answering](https://mlsanity.com/paper/2003.10286/) (2020)
- [PMC-VQA: Visual Instruction Tuning for Medical Visual Question Answering](https://mlsanity.com/paper/2305.10415/) (2023)
- [Qwen2.5-1M Technical Report](https://mlsanity.com/paper/2501.15383/) (2025)
- [An open access repository of images on plant health to enable the development of mobile disease diagnostics](https://mlsanity.com/paper/1511.08060/) (2015)
- [MedCoT: Medical Chain of Thought via Hierarchical Expert](https://mlsanity.com/paper/2412.13736/) (2024)
- [Bias Is a Subspace, Not a Coordinate: A Geometric Rethinking of Post-hoc Debiasing in Vision-Language Models](https://mlsanity.com/paper/2511.18123/) (2025)

## Abstract (arXiv)

Vision evaluations are typically done through multi-step processes. In most contemporary fields, experts analyze images using structured, evidence-based adaptive questioning. In plant pathology, botanists inspect leaf images, identify visual cues, infer diagnostic intent, and probe further with targeted questions that adapt to species, symptoms, and severity. This structured probing is crucial for accurate disease diagnosis and treatment formulation. Yet current vision-language models are evaluated on single-turn question answering. To address this gap, we introduce PlantInquiryVQA, a benchmark for studying multi-step, intent-driven visual reasoning in botanical diagnosis. We formalize a Chain of Inquiry framework modeling diagnostic trajectories as ordered question-answer sequences conditioned on grounded visual cues and explicit epistemic intent. We release a dataset of 24,950 expert-curated plant images and 138,068 question-answer pairs annotated with visual grounding, severity labels, and domain-specific reasoning templates. Evaluations on top-tier Multimodal Large Language Models reveal that while they describe visual symptoms adequately, they struggle with safe clinical reasoning and accurate diagnosis. Importantly, structured question-guided inquiry significantly improves diagnostic correctness, reduces hallucination, and increases reasoning efficiency. We hope PlantInquiryVQA serves as a foundational benchmark in advancing research to train diagnostic agents to reason like expert botanists rather than static classifiers.