# Bridging Foundation Models and ASTM Metallurgical Standards for Automated Grain Size Estimation from Microscopy Images

arXiv: https://arxiv.org/abs/2604.18957 · HTML: https://mlsanity.com/paper/2604.18957/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 8 of its 35 references that are in the map.
- First posted on arXiv 21 Apr 2026.

## Builds on (most cited first, 8 of 8)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [Pretrained Transformers Improve Out-of-Distribution Robustness](https://mlsanity.com/paper/2004.06100/) (2020)
- [NaturalBench: Evaluating Vision-Language Models on Natural Adversarial Samples](https://mlsanity.com/paper/2410.14669/) (2024)
- [Vision Language Models are Biased](https://mlsanity.com/paper/2505.23941/) (2025)
- [LVLM-COUNT: Enhancing the Counting Ability of Large Vision-Language Models](https://mlsanity.com/paper/2412.00686/) (2024)
- [Optimized and autonomous machine learning framework for characterizing pores, particles, grains and grain boundaries in microstructural images](https://mlsanity.com/paper/2101.06474/) (2021)
- [Grain and Grain Boundary Segmentation using Machine Learning with Real and Generated Datasets](https://mlsanity.com/paper/2307.05911/) (2023)

## Abstract (arXiv)

Extracting standardized metallurgical metrics from microscopy images remains challenging due to complex grain morphology and the data demands of supervised segmentation. To bridge foundational computer vision with practical metallurgical evaluation, we propose an automated pipeline for dense instance segmentation and grain size estimation that adapts Cellpose-SAM to microstructures and integrates its topology-aware gradient tracking with an ASTM E112 Jeffries planimetric module. We systematically benchmark this pipeline against a classical convolutional network (U-Net), an adaptive-prompting vision foundation model (MatSAM) and a contemporary vision-language model (Qwen2.5-VL-7B). Our evaluations reveal that while the out-of-the-box vision-language model struggles with the localized spatial reasoning required for dense microscopic counting and MatSAM suffers from over-segmentation despite its domain-specific prompt generation, our adapted pipeline successfully maintains topological separation. Furthermore, experiments across progressively reduced training splits demonstrate exceptional few-shot scalability; utilizing only two training samples, the proposed system predicts the ASTM grain size number (G) with a mean absolute percentage error (MAPE) as low as 1.50%, while robustness testing across varying target grain counts empirically validates the ASTM 50-grain sampling minimum. These results highlight the efficacy of application-level foundation model integration for highly accurate, automated materials characterization. Our project repository is available at https://github.com/mueez-overflow/ASTM-Grain-Size-Estimator.