# Trustworthy Endoscopic Super-Resolution

arXiv: https://arxiv.org/abs/2604.18001 · HTML: https://mlsanity.com/paper/2604.18001/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 34 of its 48 references that are in the map.
- First posted on arXiv 20 Apr 2026.

## Builds on (most cited first, 30 of 34)

- [On Calibration of Modern Neural Networks](https://mlsanity.com/paper/1706.04599/) (2017)
- [Dropout as a Bayesian Approximation: Representing Model Uncertainty in Deep Learning](https://mlsanity.com/paper/1506.02142/) (2015)
- [Simple and Scalable Predictive Uncertainty Estimation using Deep Ensembles](https://mlsanity.com/paper/1612.01474/) (2016)
- [A Baseline for Detecting Misclassified and Out-of-Distribution Examples in Neural Networks](https://mlsanity.com/paper/1610.02136/) (2016)
- [SwinIR: Image Restoration Using Swin Transformer](https://mlsanity.com/paper/2108.10257/) (2021)
- [Conformalized Quantile Regression](https://mlsanity.com/paper/1905.03222/) (2019)
- [Conformal Prediction Under Covariate Shift](https://mlsanity.com/paper/1904.06019/) (2019)
- [Uncertainty Sets for Image Classifiers using Conformal Prediction](https://mlsanity.com/paper/2009.14193/) (2020)
- [Conformal prediction beyond exchangeability](https://mlsanity.com/paper/2202.13415/) (2022)
- [BasicVSR++: Improving Video Super-Resolution with Enhanced Propagation and Alignment](https://mlsanity.com/paper/2104.13371/) (2021)
- [BasicVSR: The Search for Essential Components in Video Super-Resolution and Beyond](https://mlsanity.com/paper/2012.02181/) (2020)
- [Conformal Risk Control](https://mlsanity.com/paper/2208.02814/) (2022)
- [Least Ambiguous Set-Valued Classifiers with Bounded Error Levels](https://mlsanity.com/paper/1609.00451/) (2016)
- [Single Image Super-Resolution via a Holistic Attention Network](https://mlsanity.com/paper/2008.08767/) (2020)
- [Addressing Failure Prediction by Learning Model Confidence](https://mlsanity.com/paper/1910.04851/) (2019)
- [Learning by Transduction](https://mlsanity.com/paper/1301.7375/) (2013)
- [Class-Conditional Conformal Prediction with Many Classes](https://mlsanity.com/paper/2306.09335/) (2023)
- [Image-to-Image Regression with Distribution-Free Uncertainty Quantification and Applications in Imaging](https://mlsanity.com/paper/2202.05265/) (2022)
- [Fair Conformal Predictors for Applications in Medical Imaging](https://mlsanity.com/paper/2109.04392/) (2021)
- [DOCTOR: A Simple Method for Detecting Misclassification Errors](https://mlsanity.com/paper/2106.02395/) (2021)
- [How to Trust Your Diffusion Model: A Convex Optimization Approach to Conformal Risk Control](https://mlsanity.com/paper/2302.03791/) (2023)
- [Improving Trustworthiness of AI Disease Severity Rating in Medical Imaging with Ordinal Conformal Prediction Sets](https://mlsanity.com/paper/2207.02238/) (2022)
- [Confidence Estimation via Auxiliary Models](https://mlsanity.com/paper/2012.06508/) (2020)
- [Kandinsky Conformal Prediction: Efficient Calibration of Image Segmentation Algorithms](https://mlsanity.com/paper/2311.11837/) (2023)
- [Conformal Prediction for Image Segmentation Using Morphological Prediction Sets](https://mlsanity.com/paper/2503.05618/) (2025)
- [Full Conformal Adaptation of Medical Vision-Language Models](https://mlsanity.com/paper/2506.06076/) (2025)
- [ViLU: Learning Vision-Language Uncertainties for Failure Prediction](https://mlsanity.com/paper/2507.07620/) (2025)
- [Conformal Risk Control for Semantic Uncertainty Quantification in Computed Tomography](https://mlsanity.com/paper/2503.00136/) (2025)
- [Trustworthy Few-Shot Transfer of Medical VLMs through Split Conformal Prediction](https://mlsanity.com/paper/2506.17503/) (2025)
- [Pitfalls of Conformal Predictions for Medical Image Classification](https://mlsanity.com/paper/2506.18162/) (2025)

## Abstract (arXiv)

Super-resolution (SR) models are attracting growing interest for enhancing minimally invasive surgery and diagnostic videos under hardware constraints. However, valid concerns remain regarding the introduction of hallucinated structures and amplified noise, limiting their reliability in safety-critical settings. We propose a direct and practical framework to make SR systems more trustworthy by identifying where reconstructions are likely to fail. Our approach integrates a lightweight error-prediction network that operates on intermediate representations to estimate pixel-wise reconstruction error. The module is computationally efficient and low-latency, making it suitable for real-time deployment. We convert these predictions into operational failure decisions by constructing Conformal Failure Masks (CFM), which localize regions where the SR output should not be trusted. Built on conformal risk control principles, our method provides theoretical guarantees for controlling both the tolerated error limit and the miscoverage in detected failures. We evaluate our approach on image and video SR, demonstrating its effectiveness in detecting unreliable reconstructions in endoscopic and robotic surgery settings. To our knowledge, this is the first study to provide a model-agnostic, theoretically grounded approach to improving the safety of real-time endoscopic image SR.