# PA-TCNet: Pathology-Aware Temporal Calibration with Physiology-Guided Target Refinement for Cross-Subject Motor Imagery EEG Decoding in Stroke Patients

arXiv: https://arxiv.org/abs/2604.16554 · HTML: https://mlsanity.com/paper/2604.16554/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 4 of its 29 references that are in the map.
- First posted on arXiv 17 Apr 2026.

## Builds on (most cited first, 4 of 4)

- [A Tale of Single-channel Electroencephalogram: Devices, Datasets, Signal Processing, Applications, and Future Directions](https://mlsanity.com/paper/2407.14850/) (2024)
- [DBConformer: Dual-Branch Convolutional Transformer for EEG Decoding](https://mlsanity.com/paper/2506.21140/) (2025)
- [SlimSeiz: Efficient Channel-Adaptive Seizure Prediction Using a Mamba-Enhanced Network](https://mlsanity.com/paper/2410.09998/) (2024)
- [SSAS: Cross-subject EEG-based Emotion Recognition through Source Selection with Adversarial Strategy](https://mlsanity.com/paper/2512.13458/) (2025)

## Built on by (most cited first, 1 of 1)

- [Virtual iEEG from Scalp EEG: Charting the Landscape of Source Imaging, Intracranial Inference and Reconstruction](https://mlsanity.com/paper/2608.26998/) (2026)

## Abstract (arXiv)

Stroke patient cross-subject electroencephalography (EEG) decoding of motor imagery (MI) brain-computer interface (BCI) is essential for motor rehabilitation, yet lesion-related abnormal temporal dynamics and pronounced inter-patient heterogeneity often undermine generalization. Existing adaptation methods are easily misled by pathological slow-wave activity and unstable target-domain pseudo-labels. To address this challenge, we propose PA-TCNet, a pathology-aware temporal calibration framework with physiology-guided target refinement for stroke motor imagery decoding. PA-TCNet integrates two coordinated components. The Pathology-aware Rhythmic State Mamba (PRSM) module decomposes EEG spatiotemporal features into slowly varying rhythmic context and fast transient perturbations, injecting the fused pathological context into selective state propagation to more effectively capture abnormal temporal dynamics. The Physiology-Guided Target Calibration (PGTC) module constructs source-domain sensorimotor region-of-interest templates, imposing physiological consistency constraints and dynamically refining target-domain pseudo-labels, thereby improving adaptation reliability. Leave-one-subject-out experiments on two independent stroke EEG datasets, XW-Stroke and 2019-Stroke, yielded mean accuracies of 66.56% and 72.75%, respectively, outperforming state-of-the-art baselines. These results indicate that jointly modeling pathological temporal dynamics and physiology-constrained pseudo-supervision can provide more robust cross-subject initialization for personalized post-stroke MI-BCI rehabilitation. The implemented code is available at https://github.com/wxk1224/PA-TCNet.