# Personalized and Context-Aware Transformer Models for Predicting Post-Intervention Physiological Responses from Wearable Sensor Data

arXiv: https://arxiv.org/abs/2604.14738 · HTML: https://mlsanity.com/paper/2604.14738/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 4 of its 39 references that are in the map.
- First posted on arXiv 16 Apr 2026.

## Builds on (most cited first, 4 of 4)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Selective Classification for Deep Neural Networks](https://mlsanity.com/paper/1705.08500/) (2017)
- [Temporal Fusion Transformers for Interpretable Multi-horizon Time Series Forecasting](https://mlsanity.com/paper/1912.09363/) (2019)
- [Momentary Stressor Logging and Reflective Visualizations: Implications for Stress Management with Wearables](https://mlsanity.com/paper/2401.16307/) (2024)

## Abstract (arXiv)

Consumer wearables enable continuous measurement of physiological data related to stress and recovery, but turning these streams into actionable, personalized stress-management recommendations remains a challenge. In practice, users often do not know how a given intervention, defined as an activity intended to reduce stress, will affect heart rate (HR), heart rate variability (HRV), or inter-beat intervals (BBI) over the next 15 to 120 minutes. We present a framework that predicts post-intervention trajectories and the direction of change for these physiological indicators across time windows. Our methodology combines a Transformer model for multi-horizon trajectories of percent change relative to a pre-intervention baseline, direction-of-change calls (positive, negative, or neutral) at each horizon, and an empirical study using wearable sensor data overlaid with user-tagged events and interventions. This proof of concept shows that personalized post-intervention prediction is feasible. We encourage future integration into stress-management tools for personalized intervention recommendations tailored to each person's day following further validation in larger studies and, where applicable, appropriate regulatory review.