# Towards Patient-Specific Deformable Registration in Laparoscopic Surgery

arXiv: https://arxiv.org/abs/2604.13186 · HTML: https://mlsanity.com/paper/2604.13186/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 7 of its 19 references that are in the map.
- First posted on arXiv 14 Apr 2026.

## Builds on (most cited first, 7 of 7)

- [KPConv: Flexible and Deformable Convolution for Point Clouds](https://mlsanity.com/paper/1904.08889/) (2019)
- [CoFiNet: Reliable Coarse-to-fine Correspondences for Robust Point Cloud Registration](https://mlsanity.com/paper/2110.14076/) (2021)
- [REGTR: End-to-end Point Cloud Correspondences with Transformers](https://mlsanity.com/paper/2203.14517/) (2022)
- [Lepard: Learning partial point cloud matching in rigid and deformable scenes](https://mlsanity.com/paper/2111.12591/) (2021)
- [USIP: Unsupervised Stable Interest Point Detection from 3D Point Clouds](https://mlsanity.com/paper/1904.00229/) (2019)
- [EndoSurf: Neural Surface Reconstruction of Deformable Tissues with Stereo Endoscope Videos](https://mlsanity.com/paper/2307.11307/) (2023)
- [Learning Feature Descriptors for Pre- and Intra-operative Point Cloud Matching for Laparoscopic Liver Registration](https://mlsanity.com/paper/2211.03688/) (2022)

## Abstract (arXiv)

Unsafe surgical care is a critical health concern, often linked to limitations in surgeon experience, skills, and situational awareness. Integrating patient-specific 3D models into the surgical field can enhance visualization, provide real-time anatomical guidance, and reduce intraoperative complications. However, reliably registering these models in general surgery remains challenging due to mismatches between preoperative and intraoperative organ surfaces, such as deformations and noise. To overcome these challenges, we introduce the first patient-specific non-rigid point cloud registration method, which leverages a novel data generation strategy to optimize outcomes for individual patients. Our approach combines a Transformer encoder-decoder architecture with overlap estimation and a dedicated matching module to predict dense correspondences, followed by a physics-based algorithm for registration. Experimental results on both synthetic and real data demonstrate that our patient-specific method significantly outperforms traditional agnostic approaches, achieving 45% Matching Score with 92% Inlier Ratio on synthetic data, highlighting its potential to improve surgical care.