# Multiple Domain Generalization Using Category Information Independent of Domain Differences

arXiv: https://arxiv.org/abs/2604.07175 · HTML: https://mlsanity.com/paper/2604.07175/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 18 of its 25 references that are in the map.
- First posted on arXiv 8 Apr 2026.

## Builds on (most cited first, 18 of 18)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Neural Discrete Representation Learning](https://mlsanity.com/paper/1711.00937/) (2017)
- [Categorical Reparameterization with Gumbel-Softmax](https://mlsanity.com/paper/1611.01144/) (2016)
- [Masked-attention Mask Transformer for Universal Image Segmentation](https://mlsanity.com/paper/2112.01527/) (2021)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [SegNet: A Deep Convolutional Encoder-Decoder Architecture for Image Segmentation](https://mlsanity.com/paper/1511.00561/) (2015)
- [Deep High-Resolution Representation Learning for Visual Recognition](https://mlsanity.com/paper/1908.07919/) (2019)
- [Two at Once: Enhancing Learning and Generalization Capacities via IBN-Net](https://mlsanity.com/paper/1807.09441/) (2018)
- [RobustNet: Improving Domain Generalization in Urban-Scene Segmentation via Instance Selective Whitening](https://mlsanity.com/paper/2103.15597/) (2021)
- [UCTransNet: Rethinking the Skip Connections in U-Net from a Channel-wise Perspective with Transformer](https://mlsanity.com/paper/2109.04335/) (2021)
- [ONE-PEACE: Exploring One General Representation Model Toward Unlimited Modalities](https://mlsanity.com/paper/2305.11172/) (2023)
- [WildNet: Learning Domain Generalized Semantic Segmentation from the Wild](https://mlsanity.com/paper/2204.01446/) (2022)
- [SQ-VAE: Variational Bayes on Discrete Representation with Self-annealed Stochastic Quantization](https://mlsanity.com/paper/2205.07547/) (2022)
- [Efficient Semantic Video Segmentation with Per-frame Inference](https://mlsanity.com/paper/2002.11433/) (2020)
- [Global and Local Texture Randomization for Synthetic-to-Real Semantic Segmentation](https://mlsanity.com/paper/2108.02376/) (2021)
- [Semantic Self-adaptation: Enhancing Generalization with a Single Sample](https://mlsanity.com/paper/2208.05788/) (2022)
- [Feedback U-net for Cell Image Segmentation](https://mlsanity.com/paper/2004.14581/) (2020)
- [Localized Feature Aggregation Module for Semantic Segmentation](https://mlsanity.com/paper/2112.01702/) (2021)

## Abstract (arXiv)

Domain generalization is a technique aimed at enabling models to maintain high accuracy when applied to new environments or datasets (unseen domains) that differ from the datasets used in training. Generally, the accuracy of models trained on a specific dataset (source domain) often decreases significantly when evaluated on different datasets (target domain). This issue arises due to differences in domains caused by varying environmental conditions such as imaging equipment and staining methods. Therefore, we undertook two initiatives to perform segmentation that does not depend on domain differences. We propose a method that separates category information independent of domain differences from the information specific to the source domain. By using information independent of domain differences, our method enables learning the segmentation targets (e.g., blood vessels and cell nuclei). Although we extract independent information of domain differences, this cannot completely bridge the domain gap between training and test data. Therefore, we absorb the domain gap using the quantum vectors in Stochastically Quantized Variational AutoEncoder (SQ-VAE). In experiments, we evaluated our method on datasets for vascular segmentation and cell nucleus segmentation. Our methods improved the accuracy compared to conventional methods.