# A Patch-based Cross-view Regularized Framework for Backdoor Defense in Multimodal Large Language Models

arXiv: https://arxiv.org/abs/2604.04488 · HTML: https://mlsanity.com/paper/2604.04488/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in MLLM jailbreaks and adversarial robustness, one of 16 directions in Multimodal LLMs / vision-language models.
- Builds on 76 of its 96 references that are in the map.
- First posted on arXiv 6 Apr 2026.

## Placed in

- Multimodal LLMs / vision-language models / [MLLM jailbreaks and adversarial robustness](https://mlsanity.com/mllm/mllm-jailbreaks-and-adversarial-robustness/)
- LLM safety and security / [Backdoor and data poisoning attacks](https://mlsanity.com/safety/backdoor-and-data-poisoning-attacks/)

## Builds on (most cited first, 30 of 76)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Visual Instruction Tuning](https://mlsanity.com/paper/2304.08485/) (2023)
- [BLIP-2: Bootstrapping Language-Image Pre-training with Frozen Image Encoders and Large Language Models](https://mlsanity.com/paper/2301.12597/) (2023)
- [On Calibration of Modern Neural Networks](https://mlsanity.com/paper/1706.04599/) (2017)
- [Flamingo: a Visual Language Model for Few-Shot Learning](https://mlsanity.com/paper/2204.14198/) (2022)
- [Scaling Up Visual and Vision-Language Representation Learning With Noisy Text Supervision](https://mlsanity.com/paper/2102.05918/) (2021)
- [InstructBLIP: Towards General-purpose Vision-Language Models with Instruction Tuning](https://mlsanity.com/paper/2305.06500/) (2023)
- [MiniGPT-4: Enhancing Vision-Language Understanding with Advanced Large Language Models](https://mlsanity.com/paper/2304.10592/) (2023)
- [FixMatch: Simplifying Semi-Supervised Learning with Consistency and Confidence](https://mlsanity.com/paper/2001.07685/) (2020)
- [PaLM-E: An Embodied Multimodal Language Model](https://mlsanity.com/paper/2303.03378/) (2023)
- [BadNets: Identifying Vulnerabilities in the Machine Learning Model Supply Chain](https://mlsanity.com/paper/1708.06733/) (2017)
- [Kosmos-2: Grounding Multimodal Large Language Models to the World](https://mlsanity.com/paper/2306.14824/) (2023)
- [Targeted Backdoor Attacks on Deep Learning Systems Using Data Poisoning](https://mlsanity.com/paper/1712.05526/) (2017)
- [Virtual Adversarial Training: A Regularization Method for Supervised and Semi-Supervised Learning](https://mlsanity.com/paper/1704.03976/) (2017)
- [AugMix: A Simple Data Processing Method to Improve Robustness and Uncertainty](https://mlsanity.com/paper/1912.02781/) (2019)
- [Large Language Models](https://mlsanity.com/paper/2307.05782/) (2023)
- [Fine-Pruning: Defending Against Backdooring Attacks on Deep Neural Networks](https://mlsanity.com/paper/1805.12185/) (2018)
- [OpenFlamingo: An Open-Source Framework for Training Large Autoregressive Vision-Language Models](https://mlsanity.com/paper/2308.01390/) (2023)
- [Otter: A Multi-Modal Model with In-Context Instruction Tuning](https://mlsanity.com/paper/2305.03726/) (2023)
- [DriveLM: Driving with Graph Visual Question Answering](https://mlsanity.com/paper/2312.14150/) (2023)
- [Sleeper Agents: Training Deceptive LLMs that Persist Through Safety Training](https://mlsanity.com/paper/2401.05566/) (2024)
- [Regularizing Neural Networks by Penalizing Confident Output Distributions](https://mlsanity.com/paper/1701.06548/) (2017)
- [STRIP: A Defence Against Trojan Attacks on Deep Neural Networks](https://mlsanity.com/paper/1902.06531/) (2019)
- [Detecting Backdoor Attacks on Deep Neural Networks by Activation Clustering](https://mlsanity.com/paper/1811.03728/) (2018)
- [Med-Flamingo: a Multimodal Medical Few-shot Learner](https://mlsanity.com/paper/2307.15189/) (2023)
- [Input-Aware Dynamic Backdoor Attack](https://mlsanity.com/paper/2010.08138/) (2020)
- [Adversarial Neuron Pruning Purifies Backdoored Deep Models](https://mlsanity.com/paper/2110.14430/) (2021)
- [Hidden Killer: Invisible Textual Backdoor Attacks with Syntactic Trigger](https://mlsanity.com/paper/2105.12400/) (2021)
- [BadCLIP: Dual-Embedding Guided Backdoor Attack on Multimodal Contrastive Learning](https://mlsanity.com/paper/2311.12075/) (2023)

## Abstract (arXiv)

Multimodal large language models have become an important infrastructure for unified processing of visual and linguistic tasks. However, such models are highly susceptible to backdoor implantation during supervised fine-tuning and will steadily output the attacker's predefined harmful responses once a specific trigger pattern is activated. The core challenge of backdoor defense lies in suppressing attack success under low poisoning ratios while preserving the model's normal generation ability. These two objectives are inherently conflicting. Strong suppression often degrades benign performance, whereas weak regularization fails to mitigate backdoor behaviors. To this end, we propose a unified defense framework based on patch augmentation and cross-view regularity, which simultaneously constrains the model's anomalous behaviors in response to triggered patterns from both the feature representation and output distribution levels. Specifically, patch-level data augmentation is combined with cross-view output difference regularization to exploit the fact that backdoor responses are abnormally invariant to non-semantic perturbations and to proactively pull apart the output distributions of the original and perturbed views, thereby significantly suppressing the success rate of backdoor triggering. At the same time, we avoid over-suppression of the model during defense by imposing output entropy constraints, ensuring the quality of normal command generation. Experimental results across three models, two tasks, and six attacks show that our proposed defense method effectively reduces the attack success rate while maintaining a high level of normal text generation capability. Our work enables the secure, controlled deployment of large-scale multimodal models in realistic low-frequency poisoning and covert triggering scenarios.