# CXR-LT 2026 Challenge: Projection-Aware Multi-Label and Zero-Shot Chest X-Ray Classification

arXiv: https://arxiv.org/abs/2604.02185 · HTML: https://mlsanity.com/paper/2604.02185/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 17 of its 21 references that are in the map.
- First posted on arXiv 2 Apr 2026.

## Builds on (most cited first, 17 of 17)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [A ConvNet for the 2020s](https://mlsanity.com/paper/2201.03545/) (2022)
- [CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison](https://mlsanity.com/paper/1901.07031/) (2019)
- [Swin Transformer V2: Scaling Up Capacity and Resolution](https://mlsanity.com/paper/2111.09883/) (2021)
- [Going deeper with Image Transformers](https://mlsanity.com/paper/2103.17239/) (2021)
- [ConvNeXt V2: Co-designing and Scaling ConvNets with Masked Autoencoders](https://mlsanity.com/paper/2301.00808/) (2023)
- [CheXNet: Radiologist-Level Pneumonia Detection on Chest X-Rays with Deep Learning](https://mlsanity.com/paper/1711.05225/) (2017)
- [Asymmetric Loss For Multi-Label Classification](https://mlsanity.com/paper/2009.14119/) (2020)
- [What does a platypus look like? Generating customized prompts for zero-shot image classification](https://mlsanity.com/paper/2209.03320/) (2022)
- [Weakly Supervised Lesion Localization With Probabilistic-CAM Pooling](https://mlsanity.com/paper/2005.14480/) (2020)
- [BiomedCoOp: Learning to Prompt for Biomedical Vision-Language Models](https://mlsanity.com/paper/2411.15232/) (2024)
- [Vision Transformer using Low-level Chest X-ray Feature Corpus for COVID-19 Diagnosis and Severity Quantification](https://mlsanity.com/paper/2104.07235/) (2021)
- [Overview of the CXR-LT 2026 Challenge: Multi-Center Long-Tailed and Zero Shot Chest X-ray Classification](https://mlsanity.com/paper/2602.22092/) (2026)

## Built on by (most cited first, 1 of 1)

- [CXR-LT 2026 Challenge: Multi-Center Long-Tailed and Zero Shot Chest X-ray Classification](https://mlsanity.com/paper/2604.15555/) (2026)

## Abstract (arXiv)

This challenge tackles multi-label classification for known chest X-ray (CXR) lesions and zero-shot classification for unseen ones. To handle diverse CXR projections, we integrate projection-specific models via a classification network into a unified framework. For zero-shot classification (Task 2), we extend CheXzero with a novel dual-branch architecture that combines contrastive learning, Asymmetric Loss (ASL), and LLM-generated descriptive prompts. This effectively mitigates severe long-tail imbalances and maximizes zero-shot generalization. Additionally, strong data and test-time augmentations (TTA) ensure robustness across both tasks.
