# Understand and Accelerate Memory Processing Pipeline for Large Language Model Inference

arXiv: https://arxiv.org/abs/2603.29002 · HTML: https://mlsanity.com/paper/2603.29002/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Generation and context integration, one of 15 directions in Retrieval-augmented generation.
- Builds on 48 of its 61 references that are in the map.
- First posted on arXiv 30 Mar 2026.

## Placed in

- Retrieval-augmented generation / [Generation and context integration](https://mlsanity.com/rag/generation-and-context-integration/)

## Builds on (most cited first, 30 of 48)

- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Qwen3 Technical Report](https://mlsanity.com/paper/2505.09388/) (2025)
- [Efficient Memory Management for Large Language Model Serving with PagedAttention](https://mlsanity.com/paper/2309.06180/) (2023)
- [Mamba: Linear-Time Sequence Modeling with Selective State Spaces](https://mlsanity.com/paper/2312.00752/) (2023)
- [Gemini 2.5: Pushing the Frontier with Advanced Reasoning, Multimodality, Long Context, and Next Generation Agentic Capabilities](https://mlsanity.com/paper/2507.06261/) (2025)
- [Longformer: The Long-Document Transformer](https://mlsanity.com/paper/2004.05150/) (2020)
- [Tree of Thoughts: Deliberate Problem Solving with Large Language Models](https://mlsanity.com/paper/2305.10601/) (2023)
- [Voyager: An Open-Ended Embodied Agent with Large Language Models](https://mlsanity.com/paper/2305.16291/) (2023)
- [Qwen2 Technical Report](https://mlsanity.com/paper/2407.10671/) (2024)
- [Reformer: The Efficient Transformer](https://mlsanity.com/paper/2001.04451/) (2020)
- [gpt-oss-120b & gpt-oss-20b Model Card](https://mlsanity.com/paper/2508.10925/) (2025)
- [DeepSeek-V2: A Strong, Economical, and Efficient Mixture-of-Experts Language Model](https://mlsanity.com/paper/2405.04434/) (2024)
- [Interleaving Retrieval with Chain-of-Thought Reasoning for Knowledge-Intensive Multi-Step Questions](https://mlsanity.com/paper/2212.10509/) (2022)
- [RWKV: Reinventing RNNs for the Transformer Era](https://mlsanity.com/paper/2305.13048/) (2023)
- [DeepSeek-V3.2: Pushing the Frontier of Open Large Language Models](https://mlsanity.com/paper/2512.02556/) (2025)
- [FlexGen: High-Throughput Generative Inference of Large Language Models with a Single GPU](https://mlsanity.com/paper/2303.06865/) (2023)
- [Gated Delta Networks: Improving Mamba2 with Delta Rule](https://mlsanity.com/paper/2412.06464/) (2024)
- [Active Retrieval Augmented Generation](https://mlsanity.com/paper/2305.06983/) (2023)
- [MInference 1.0: Accelerating Pre-filling for Long-Context LLMs via Dynamic Sparse Attention](https://mlsanity.com/paper/2407.02490/) (2024)
- [Learning to (Learn at Test Time): RNNs with Expressive Hidden States](https://mlsanity.com/paper/2407.04620/) (2024)
- [Titans: Learning to Memorize at Test Time](https://mlsanity.com/paper/2501.00663/) (2024)
- [Atom: Low-bit Quantization for Efficient and Accurate LLM Serving](https://mlsanity.com/paper/2310.19102/) (2023)
- [MemAgent: Reshaping Long-Context LLM with Multi-Conv RL-based Memory Agent](https://mlsanity.com/paper/2507.02259/) (2025)
- [Chain-of-Thought Reasoning Without Prompting](https://mlsanity.com/paper/2402.10200/) (2024)
- [Recurrent Memory Transformer](https://mlsanity.com/paper/2207.06881/) (2022)
- [Test-Time Training Done Right](https://mlsanity.com/paper/2505.23884/) (2025)
- [SeerAttention: Learning Intrinsic Sparse Attention in Your LLMs](https://mlsanity.com/paper/2410.13276/) (2024)

## Abstract (arXiv)

Modern large language models (LLMs) increasingly depends on efficient long-context processing and generation mechanisms, including sparse attention, retrieval-augmented generation (RAG), and compressed contextual memory, to support complex reasoning. We show that these optimizations can be unified into a four-step memory processing pipeline: Prepare Memory, Compute Relevancy, Retrieval, and Apply to Inference. Through systematic profiling, we identify a 22%-97% memory processing overhead in LLM inference and strong heterogeneity in its computational characteristics. Motivated by this insight, we argue that heterogeneous systems are well-suited to accelerate memory processing and thus end-to-end inference. We demonstrate this approach on a GPU-FPGA system by offloading sparse, irregular, and memory-bounded operations to FPGAs while retaining compute-intensive operations on GPUs. Evaluated on an AMD MI210 GPU and an Alveo U55C FPGA, our system is up to 2.2× faster and achieves up to 4.7× less energy across multiple LLM inference optimizations than the GPU baseline (similar results hold on NVIDIA A100). These results establish heterogeneous systems as a practical direction for efficient LLM memory processing and inform future heterogeneous hardware design.