# Curriculum-Guided Myocardial Scar Segmentation for Ischemic and Non-ischemic Cardiomyopathy

arXiv: https://arxiv.org/abs/2603.28560 · HTML: https://mlsanity.com/paper/2603.28560/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 7 of its 19 references that are in the map.
- First posted on arXiv 30 Mar 2026.

## Builds on (most cited first, 7 of 7)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [Joint Deep Learning for Improved Myocardial Scar Detection from Cardiac MRI](https://mlsanity.com/paper/2211.06247/) (2022)
- [Robust Deep Learning for Myocardial Scar Segmentation in Cardiac MRI with Noisy Labels](https://mlsanity.com/paper/2506.21151/) (2025)
- [ScarNet: A Novel Foundation Model for Automated Myocardial Scar Quantification from LGE in Cardiac MRI](https://mlsanity.com/paper/2501.01372/) (2025)

## Built on by (most cited first, 1 of 1)

- [CalcSeg: Confidence-aware 3D Latent Context Curriculum Learning For Myocardial Scar Segmentation From Single-Stack LGE-CMRs](https://mlsanity.com/paper/2608.20305/) (2026)

## Abstract (arXiv)

Identification and quantification of myocardial scar is important for diagnosis and prognosis of cardiovascular diseases. However, reliable scar segmentation from Late Gadolinium Enhancement Cardiac Magnetic Resonance (LGE-CMR) images remains a challenge due to variations in contrast enhancement across patients, suboptimal imaging conditions such as post contrast washout, and inconsistencies in ground truth annotations on diffuse scars caused by inter observer variability. In this work, we propose a curriculum learning-based framework designed to improve segmentation performance under these challenging conditions. The method introduces a progressive training strategy that guides the model from high-confidence, clearly defined scar regions to low confidence or visually ambiguous samples with limited scar burden. By structuring the learning process in this manner, the network develops robustness to uncertain labels and subtle scar appearances that are often underrepresented in conventional training pipelines. Experimental results show that the proposed approach enhances segmentation accuracy and consistency, particularly for cases with minimal or diffuse scar, outperforming standard training baselines. This strategy provides a principled way to leverage imperfect data for improved myocardial scar quantification in clinical applications. Our code is publicly available on GitHub.
