# Domain-Guided YOLO26 with Composite BCE-Dice-Lov'asz Loss for Multi-Class Fetal Head Ultrasound Segmentation

arXiv: https://arxiv.org/abs/2603.26755 · HTML: https://mlsanity.com/paper/2603.26755/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 24 of its 38 references that are in the map.
- First posted on arXiv 23 Mar 2026.

## Builds on (most cited first, 24 of 24)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [Mask R-CNN](https://mlsanity.com/paper/1703.06870/) (2017)
- [Batch Normalization: Accelerating Deep Network Training by Reducing Internal Covariate Shift](https://mlsanity.com/paper/1502.03167/) (2015)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [SGDR: Stochastic Gradient Descent with Warm Restarts](https://mlsanity.com/paper/1608.03983/) (2016)
- [Feature Pyramid Networks for Object Detection](https://mlsanity.com/paper/1612.03144/) (2016)
- [You Only Look Once: Unified, Real-Time Object Detection](https://mlsanity.com/paper/1506.02640/) (2015)
- [Encoder-Decoder with Atrous Separable Convolution for Semantic Image Segmentation](https://mlsanity.com/paper/1802.02611/) (2018)
- [SegFormer: Simple and Efficient Design for Semantic Segmentation with Transformers](https://mlsanity.com/paper/2105.15203/) (2021)
- [UNet++: A Nested U-Net Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1807.10165/) (2018)
- [Mixed Precision Training](https://mlsanity.com/paper/1710.03740/) (2017)
- [Path Aggregation Network for Instance Segmentation](https://mlsanity.com/paper/1803.01534/) (2018)
- [The Future of Digital Health with Federated Learning](https://mlsanity.com/paper/2003.08119/) (2020)
- [Simple Copy-Paste is a Strong Data Augmentation Method for Instance Segmentation](https://mlsanity.com/paper/2012.07177/) (2020)
- [YOLACT: Real-time Instance Segmentation](https://mlsanity.com/paper/1904.02689/) (2019)
- [CSPNet: A New Backbone that can Enhance Learning Capability of CNN](https://mlsanity.com/paper/1911.11929/) (2019)
- [A Comprehensive Review of YOLO Architectures in Computer Vision: From YOLOv1 to YOLOv8 and YOLO-NAS](https://mlsanity.com/paper/2304.00501/) (2023)
- [YOLO26: Key Architectural Enhancements and Performance Benchmarking for Real-Time Object Detection](https://mlsanity.com/paper/2509.25164/) (2025)
- [A Review on Deep-Learning Algorithms for Fetal Ultrasound-Image Analysis](https://mlsanity.com/paper/2201.12260/) (2022)
- [Domain-guided data augmentation for deep learning on medical imaging](https://mlsanity.com/paper/2210.04977/) (2022)

## Abstract (arXiv)

Segmenting fetal head structures from prenatal ultrasound remains a practical bottleneck in obstetric imaging. The current state-of-the-art baseline, proposed alongside the published dataset, adapts the Segment Anything Model with per-class Dice and Lov'asz losses but still depends on bounding-box prompts at test time. We build a prompt-free pipeline on top of YOLO26-Seg that jointly detects and segments three structures, Brain, Cavum Septi Pellucidi (CSP), and Lateral Ventricles (LV), in a single forward pass. Three modifications are central to our approach: (i) a composite BCE-Dice-Lov'asz segmentation loss with inverse-frequency class weighting, injected into the YOLO26 training loop via runtime monkey-patching; (ii) domain-guided copy-paste augmentation that transplants minority-class structures while respecting their anatomical location relative to the brain boundary; and (iii) inter-patient stratified splitting to prevent data leakage. On 575 held-out test images, the composite loss variant reaches a mean Dice coefficient of 0.9253, exceeding the baseline (0.9012) by 2.68 percentage points, despite reporting over three foreground classes only, whereas the baseline's reported mean includes the easy background class. We further ablate each component and discuss annotation-quality and class-imbalance effects on CSP and LV performance.