# Refining 3D Medical Segmentation with Verbal Instruction

arXiv: https://arxiv.org/abs/2603.14496 · HTML: https://mlsanity.com/paper/2603.14496/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 17 of its 22 references that are in the map.
- First posted on arXiv 15 Mar 2026.

## Builds on (most cited first, 17 of 17)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [PointNet: Deep Learning on Point Sets for 3D Classification and Segmentation](https://mlsanity.com/paper/1612.00593/) (2016)
- [DeepSDF: Learning Continuous Signed Distance Functions for Shape Representation](https://mlsanity.com/paper/1901.05103/) (2019)
- [Implicit Neural Representations with Periodic Activation Functions](https://mlsanity.com/paper/2006.09661/) (2020)
- [Occupancy Networks: Learning 3D Reconstruction in Function Space](https://mlsanity.com/paper/1812.03828/) (2018)
- [Zero-Shot Text-Guided Object Generation with Dream Fields](https://mlsanity.com/paper/2112.01455/) (2021)
- [3DShape2VecSet: A 3D Shape Representation for Neural Fields and Generative Diffusion Models](https://mlsanity.com/paper/2301.11445/) (2023)
- [CLIP-NeRF: Text-and-Image Driven Manipulation of Neural Radiance Fields](https://mlsanity.com/paper/2112.05139/) (2021)
- [Text2Mesh: Text-Driven Neural Stylization for Meshes](https://mlsanity.com/paper/2112.03221/) (2021)
- [nnU-Net Revisited: A Call for Rigorous Validation in 3D Medical Image Segmentation](https://mlsanity.com/paper/2404.09556/) (2024)
- [The TopCoW Challenge -- Topology-Aware Circle of Willis Segmentation for CT and MR Angiography](https://mlsanity.com/paper/2312.17670/) (2023)
- [PrEditor3D: Fast and Precise 3D Shape Editing](https://mlsanity.com/paper/2412.06592/) (2024)
- [Neural Annotation Refinement: Development of a New 3D Dataset for Adrenal Gland Analysis](https://mlsanity.com/paper/2206.15328/) (2022)
- [Neural Implicit Shape Editing using Boundary Sensitivity](https://mlsanity.com/paper/2304.12951/) (2023)
- [Circle of Willis Centerline Graphs: A Dataset and Baseline Algorithm](https://mlsanity.com/paper/2510.13720/) (2025)

## Abstract (arXiv)

Accurate 3D anatomical segmentation is essential for clinical diagnosis and surgical planning. However, automated models frequently generate suboptimal shape predictions due to factors such as limited and imbalanced training data, inadequate labeling quality, and distribution shifts between training and deployment settings. A natural solution is to iteratively refine the predicted shape based on the radiologists' verbal instructions. However, this is hindered by the scarcity of paired data that explicitly links erroneous shapes to corresponding corrective instructions. As an initial step toward addressing this limitation, we introduce CoWTalk, a benchmark comprising 3D arterial anatomies with controllable synthesized anatomical errors and their corresponding repairing instructions. Building on this benchmark, we further propose an iterative refinement model that represents 3D shapes as vector sets and interacts with textual instructions to progressively update the target shape. Experimental results demonstrate that our method achieves significant improvements over corrupted inputs and competitive baselines, highlighting the feasibility of language-driven clinician-in-the-loop refinement for 3D medical shapes modeling.