# GLEAM: A Multimodal Imaging Dataset and HAMM for Glaucoma Classification

arXiv: https://arxiv.org/abs/2603.12800 · HTML: https://mlsanity.com/paper/2603.12800/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 23 of its 60 references that are in the map.
- First posted on arXiv 13 Mar 2026.

## Builds on (most cited first, 23 of 23)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Masked Autoencoders Are Scalable Vision Learners](https://mlsanity.com/paper/2111.06377/) (2021)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [On Calibration of Modern Neural Networks](https://mlsanity.com/paper/1706.04599/) (2017)
- [A ConvNet for the 2020s](https://mlsanity.com/paper/2201.03545/) (2022)
- [Supervised Contrastive Learning](https://mlsanity.com/paper/2004.11362/) (2020)
- [CBAM: Convolutional Block Attention Module](https://mlsanity.com/paper/1807.06521/) (2018)
- [Xception: Deep Learning with Depthwise Separable Convolutions](https://mlsanity.com/paper/1610.02357/) (2016)
- [MultiMAE: Multi-modal Multi-task Masked Autoencoders](https://mlsanity.com/paper/2204.01678/) (2022)
- [REFUGE Challenge: A Unified Framework for Evaluating Automated Methods for Glaucoma Assessment from Fundus Photographs](https://mlsanity.com/paper/1910.03667/) (2019)
- [Designing BERT for Convolutional Networks: Sparse and Hierarchical Masked Modeling](https://mlsanity.com/paper/2301.03580/) (2023)
- [Multimodal Intelligence: Representation Learning, Information Fusion, and Applications](https://mlsanity.com/paper/1911.03977/) (2019)
- [GAMMA Challenge:Glaucoma grAding from Multi-Modality imAges](https://mlsanity.com/paper/2202.06511/) (2022)
- [Disc-aware Ensemble Network for Glaucoma Screening from Fundus Image](https://mlsanity.com/paper/1805.07549/) (2018)
- [Harvard Glaucoma Fairness: A Retinal Nerve Disease Dataset for Fairness Learning and Fair Identity Normalization](https://mlsanity.com/paper/2306.09264/) (2023)
- [Multimodal Multi-Head Convolutional Attention with Various Kernel Sizes for Medical Image Super-Resolution](https://mlsanity.com/paper/2204.04218/) (2022)
- [Harvard Glaucoma Detection and Progression: A Multimodal Multitask Dataset and Generalization-Reinforced Semi-Supervised Learning](https://mlsanity.com/paper/2308.13411/) (2023)
- [COROLLA: An Efficient Multi-Modality Fusion Framework with Supervised Contrastive Learning for Glaucoma Grading](https://mlsanity.com/paper/2201.03795/) (2022)
- [UrFound: Towards Universal Retinal Foundation Models via Knowledge-Guided Masked Modeling](https://mlsanity.com/paper/2408.05618/) (2024)
- [Multimodal Fusion Learning with Dual Attention for Medical Imaging](https://mlsanity.com/paper/2412.01248/) (2024)
- [ELF: An End-to-end Local and Global Multimodal Fusion Framework for Glaucoma Grading](https://mlsanity.com/paper/2311.08032/) (2023)
- [ETSCL: An Evidence Theory-Based Supervised Contrastive Learning Framework for Multi-modal Glaucoma Grading](https://mlsanity.com/paper/2407.14230/) (2024)

## Abstract (arXiv)

We propose glaucoma lesion evaluation and analysis with multimodal imaging (GLEAM), the first publicly available tri-modal glaucoma dataset comprising scanning laser ophthalmoscopy fundus images, circumpapillary OCT images, and visual field pattern deviation maps, annotated with four disease stages, enabling effective exploitation of multimodal complementary information and facilitating accurate diagnosis and treatment across disease stages. To effectively integrate cross-modal information, we propose hierarchical attentive masked modeling (HAMM) for multimodal glaucoma classification. Our framework employs hierarchical attentive encoders and light decoders to focus cross-modal representation learning on the encoder.
