# Composed Vision-Language Retrieval for Skin Cancer Case Search via Joint Alignment of Global and Local Representations

arXiv: https://arxiv.org/abs/2603.09108 · HTML: https://mlsanity.com/paper/2603.09108/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 10 of its 30 references that are in the map.
- First posted on arXiv 10 Mar 2026.

## Builds on (most cited first, 10 of 10)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [RoBERTa: A Robustly Optimized BERT Pretraining Approach](https://mlsanity.com/paper/1907.11692/) (2019)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [Med-BERT: pre-trained contextualized embeddings on large-scale structured electronic health records for disease prediction](https://mlsanity.com/paper/2005.12833/) (2020)
- [BERT: A Review of Applications in Natural Language Processing and Understanding](https://mlsanity.com/paper/2103.11943/) (2021)
- [A Multimodal Vision Foundation Model for Clinical Dermatology](https://mlsanity.com/paper/2410.15038/) (2024)
- [A Comprehensive Survey on Composed Image Retrieval](https://mlsanity.com/paper/2502.18495/) (2025)
- [Diagnostic Accuracy of Content Based Dermatoscopic Image Retrieval with Deep Classification Features](https://mlsanity.com/paper/1810.09487/) (2018)
- [Integrating Clinical Knowledge Graphs and Gradient-Based Neural Systems for Enhanced Melanoma Diagnosis via the 7-Point Checklist](https://mlsanity.com/paper/2407.16822/) (2024)
- [SkinFormer: Learning Statistical Texture Representation with Transformer for Skin Lesion Segmentation](https://mlsanity.com/paper/2409.08652/) (2024)

## Abstract (arXiv)

Medical image retrieval aims to identify clinically relevant lesion cases to support diagnostic decision making, education, and quality control. In practice, retrieval queries often combine a reference lesion image with textual descriptors such as dermoscopic features. We study composed vision-language retrieval for skin cancer, where each query consists of an image to text pair and the database contains biopsy-confirmed, multi-class disease cases. We propose a transformer based framework that learns hierarchical composed query representations and performs joint global-local alignment between queries and candidate images. Local alignment aggregates discriminative regions via multiple spatial attention masks, while global alignment provides holistic semantic supervision. The final similarity is computed through a convex, domain-informed weighting that emphasizes clinically salient local evidence while preserving global consistency. Experiments on the public Derm7pt dataset demonstrate consistent improvements over state-of-the-art methods. The proposed framework enables efficient access to relevant medical records and supports practical clinical deployment.
