# AutoAdapt: An Automated Domain Adaptation Framework for LLMs

arXiv: https://arxiv.org/abs/2603.08181 · HTML: https://mlsanity.com/paper/2603.08181/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 28 of its 43 references that are in the map.
- First posted on arXiv 9 Mar 2026.

## Builds on (most cited first, 28 of 28)

- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Measuring Mathematical Problem Solving With the MATH Dataset](https://mlsanity.com/paper/2103.03874/) (2021)
- [Think you have Solved Question Answering? Try ARC, the AI2 Reasoning Challenge](https://mlsanity.com/paper/1803.05457/) (2018)
- [Program Synthesis with Large Language Models](https://mlsanity.com/paper/2108.07732/) (2021)
- [Convex optimization](https://mlsanity.com/paper/2106.01946/) (2021)
- [Optuna: A Next-generation Hyperparameter Optimization Framework](https://mlsanity.com/paper/1907.10902/) (2019)
- [Is Your Code Generated by ChatGPT Really Correct? Rigorous Evaluation of Large Language Models for Code Generation](https://mlsanity.com/paper/2305.01210/) (2023)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [HuggingGPT: Solving AI Tasks with ChatGPT and its Friends in Hugging Face](https://mlsanity.com/paper/2303.17580/) (2023)
- [A Tutorial on Bayesian Optimization](https://mlsanity.com/paper/1807.02811/) (2018)
- [GPyTorch: Blackbox Matrix-Matrix Gaussian Process Inference with GPU Acceleration](https://mlsanity.com/paper/1809.11165/) (2018)
- [Data Interpreter: An LLM Agent For Data Science](https://mlsanity.com/paper/2402.18679/) (2024)
- [When Does Pretraining Help? Assessing Self-Supervised Learning for Law and the CaseHOLD Dataset](https://mlsanity.com/paper/2104.08671/) (2021)
- [Large Language Models to Enhance Bayesian Optimization](https://mlsanity.com/paper/2402.03921/) (2024)
- [Large Language Models for Automated Data Science: Introducing CAAFE for Context-Aware Automated Feature Engineering](https://mlsanity.com/paper/2305.03403/) (2023)
- [DS-Agent: Automated Data Science by Empowering Large Language Models with Case-Based Reasoning](https://mlsanity.com/paper/2402.17453/) (2024)
- [AutoML-Agent: A Multi-Agent LLM Framework for Full-Pipeline AutoML](https://mlsanity.com/paper/2410.02958/) (2024)
- [MLCopilot: Unleashing the Power of Large Language Models in Solving Machine Learning Tasks](https://mlsanity.com/paper/2304.14979/) (2023)
- [Large Language Model Agent for Hyper-Parameter Optimization](https://mlsanity.com/paper/2402.01881/) (2024)
- [LLM Processes: Numerical Predictive Distributions Conditioned on Natural Language](https://mlsanity.com/paper/2405.12856/) (2024)
- [When2Call: When (not) to Call Tools](https://mlsanity.com/paper/2504.18851/) (2025)
- [Prompt2Model: Generating Deployable Models from Natural Language Instructions](https://mlsanity.com/paper/2308.12261/) (2023)
- [Kolb-Based Experiential Learning for Generalist Agents with Human-Level Kaggle Data Science Performance](https://mlsanity.com/paper/2411.03562/) (2024)
- [Introduction to Coresets: Accurate Coresets](https://mlsanity.com/paper/1910.08707/) (2019)
- [AutoMMLab: Automatically Generating Deployable Models from Language Instructions for Computer Vision Tasks](https://mlsanity.com/paper/2402.15351/) (2024)
- [Improved Regret Bounds for Gaussian Process Upper Confidence Bound in Bayesian Optimization](https://mlsanity.com/paper/2506.01393/) (2025)
- [Why Do Transformers Fail to Forecast Time Series In-Context?](https://mlsanity.com/paper/2510.09776/) (2025)
- [An Introduction to Gaussian Process Models](https://mlsanity.com/paper/2102.05497/) (2021)

## Abstract (arXiv)

Large language models (LLMs) excel in open domains but struggle in specialized settings with limited data and evolving knowledge. Existing domain adaptation practices rely heavily on manual trial-and-error processes, incur significant hyperparameter complexity, and are highly sensitive to data and user preferences, all under the high cost of LLM training. Moreover, the interactions and transferability of hyperparameter choices across models/domains remain poorly understood, making adaptation gains uncertain even with substantial effort. To solve these challenges, we present AutoAdapt, a novel end-to-end automated framework for efficient and reliable LLM domain adaptation. AutoAdapt leverages curated knowledge bases from literature and open-source resources to reduce expert intervention. To narrow the search space, we design a novel multi-agent debating system in which proposal and critic agents iteratively interact to align user intent and incorporate data signals and best practices into the planning process. To optimize hyperparameters under tight budgets, we propose AutoRefine, a novel LLM-based surrogate that replaces costly black-box search. Across 10 tasks, AutoAdapt achieves a 25% average relative accuracy improvement over state-of-the-art Automated Machine Learning baselines with minimal overhead.