# 3D CBCT Artefact Removal Using Perpendicular Score-Based Diffusion Models

arXiv: https://arxiv.org/abs/2603.06300 · HTML: https://mlsanity.com/paper/2603.06300/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models.
- Builds on 6 of its 20 references that are in the map.
- First posted on arXiv 6 Mar 2026.

## Placed in

- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 6 of 6)

- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Diffusion Posterior Sampling for General Noisy Inverse Problems](https://mlsanity.com/paper/2209.14687/) (2022)
- [DuDoNet: Dual Domain Network for CT Metal Artifact Reduction](https://mlsanity.com/paper/1907.00273/) (2019)
- [WDM: 3D Wavelet Diffusion Models for High-Resolution Medical Image Synthesis](https://mlsanity.com/paper/2402.19043/) (2024)
- [Improving 3D Imaging with Pre-Trained Perpendicular 2D Diffusion Models](https://mlsanity.com/paper/2303.08440/) (2023)
- [Metal Inpainting in CBCT Projections Using Score-based Generative Model](https://mlsanity.com/paper/2209.09733/) (2022)

## Abstract (arXiv)

Cone-beam computed tomography (CBCT) is a widely used 3D imaging technique in dentistry, offering high-resolution images while minimising radiation exposure for patients. However, CBCT is highly susceptible to artefacts arising from high-density objects such as dental implants, which can compromise image quality and diagnostic accuracy. To reduce artefacts, implant inpainting in the sequence of projections plays a crucial role in many artefact reduction approaches. Recently, diffusion models have achieved state-of-the-art results in image generation and have widely been applied to image inpainting tasks. However, to our knowledge, existing diffusion-based methods for implant inpainting operate on independent 2D projections. This approach neglects the correlations among individual projections, resulting in inconsistencies in the reconstructed images. To address this, we propose a 3D dental implant inpainting approach based on perpendicular score-based diffusion models, each trained in two different planes and operating in the projection domain. The 3D distribution of the projection series is modelled by combining the two 2D score-based diffusion models in the sampling scheme. Our results demonstrate the method's effectiveness in producing high-quality, artefact-reduced 3D CBCT images, making it a promising solution for improving clinical imaging.