# CRIMSON: A Clinically-Grounded LLM-Based Metric for Generative Radiology Report Evaluation

arXiv: https://arxiv.org/abs/2603.06183 · HTML: https://mlsanity.com/paper/2603.06183/

## Key facts

- Cited by 9 papers in the map (data through 14 Oct 2026).
- Builds on 20 of its 28 references that are in the map.
- First posted on arXiv 6 Mar 2026.

## Builds on (most cited first, 20 of 20)

- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [BERTScore: Evaluating Text Generation with BERT](https://mlsanity.com/paper/1904.09675/) (2019)
- [OpenAI GPT-5 System Card](https://mlsanity.com/paper/2601.03267/) (2025)
- [MedGemma Technical Report](https://mlsanity.com/paper/2507.05201/) (2025)
- [CheXbert: Combining Automatic Labelers and Expert Annotations for Accurate Radiology Report Labeling Using BERT](https://mlsanity.com/paper/2004.09167/) (2020)
- [RadGraph: Extracting Clinical Entities and Relations from Radiology Reports](https://mlsanity.com/paper/2106.14463/) (2021)
- [MAIRA-2: Grounded Radiology Report Generation](https://mlsanity.com/paper/2406.04449/) (2024)
- [GREEN: Generative Radiology Report Evaluation and Error Notation](https://mlsanity.com/paper/2405.03595/) (2024)
- [RaTEScore: A Metric for Radiology Report Generation](https://mlsanity.com/paper/2406.16845/) (2024)
- [ReXGradient-160K: A Large-Scale Publicly Available Dataset of Chest Radiographs with Free-text Reports](https://mlsanity.com/paper/2505.00228/) (2025)
- [RadEval: A framework for radiology text evaluation](https://mlsanity.com/paper/2509.18030/) (2025)
- [FineRadScore: A Radiology Report Line-by-Line Evaluation Technique Generating Corrections with Severity Scores](https://mlsanity.com/paper/2405.20613/) (2024)
- [LLM-RadJudge: Achieving Radiologist-Level Evaluation for X-Ray Report Generation](https://mlsanity.com/paper/2404.00998/) (2024)
- [ReEvalMed: Rethinking Medical Report Evaluation by Aligning Metrics with Real-World Clinical Judgment](https://mlsanity.com/paper/2510.00280/) (2025)
- [Leveraging Professional Radiologists' Expertise to Enhance LLMs' Evaluation for Radiology Reports](https://mlsanity.com/paper/2401.16578/) (2024)
- [S-RRG-Bench: Structured Radiology Report Generation with Fine-Grained Evaluation Framework](https://mlsanity.com/paper/2508.02082/) (2025)
- [CLEAR: A Clinically-Grounded Tabular Framework for Radiology Report Evaluation](https://mlsanity.com/paper/2505.16325/) (2025)
- [Exploring the Design Space of 3D MLLMs for CT Report Generation](https://mlsanity.com/paper/2506.21535/) (2025)
- [Clinically Grounded Agent-based Report Evaluation: An Interpretable Metric for Radiology Report Generation](https://mlsanity.com/paper/2508.02808/) (2025)
- [RadGame: An AI-Powered Platform for Radiology Education](https://mlsanity.com/paper/2509.13270/) (2025)

## Built on by (most cited first, 9 of 9)

- [Can Jev Judge Radiology Reports? Evaluating a System One Model for Clinical Factuality](https://mlsanity.com/paper/2609.27607/) (2026)
- [Jolia: Concept-Level Vision-Language Alignment for 3D CT Contrastive Learning](https://mlsanity.com/paper/2606.24570/) (2026)
- [RadMatch: Auditable Radiology Report Evaluation via Finding-Level Matching](https://mlsanity.com/paper/2609.01470/) (2026)
- [Beyond Scalar Scores: Exploring LLM-based Metrics for Clinical Significance Evaluation in Radiology Reports](https://mlsanity.com/paper/2606.18797/) (2026)
- [PathReportEval: A Systematic Benchmark for Pathology Report Generation](https://mlsanity.com/paper/2607.18448/) (2026)
- [CARE-X: Towards Clinically Useful Radiology VLMs with Auxiliary Supervision, Reward-Aligned Learning, and Tool-Augmented Measurement](https://mlsanity.com/paper/2608.03890/) (2026)
- [Two-Stage Mixture-of-LoRA for Multi-Task Medical Vision-Language Learning](https://mlsanity.com/paper/2609.14350/) (2026)
- [Reporting Practice Matters: The Impact of Reference Choice on Chest X-ray Report Evaluation](https://mlsanity.com/paper/2609.19093/) (2026)
- [Multimodal Medical Image Parsing with Task-Specific Low-Rank Adapters](https://mlsanity.com/paper/2610.19901/) (2026)

## Abstract (arXiv)

We introduce CRIMSON, a clinically grounded evaluation framework for chest X-ray report generation that assesses reports based on diagnostic correctness, contextual relevance, and patient safety. Unlike prior metrics, CRIMSON incorporates full clinical context, including patient age, indication, and guideline-based decision rules, and prevents normal or clinically insignificant findings from exerting disproportionate influence on the overall score. The framework categorizes errors into a comprehensive taxonomy covering false findings, missing findings, and eight attribute-level errors (e.g., location, severity, measurement, and diagnostic overinterpretation). Each finding is assigned a clinical significance level (urgent, actionable non-urgent, non-actionable, or expected/benign), based on a guideline developed in collaboration with attending cardiothoracic radiologists, enabling severity-aware weighting that prioritizes clinically consequential mistakes over benign discrepancies. CRIMSON is validated through strong alignment with clinically significant error counts annotated by six board-certified radiologists in ReXVal (Kendalls tau = 0.61-0.71; Pearsons r = 0.71-0.84), and through two additional benchmarks that we introduce. In RadJudge, a targeted suite of clinically challenging pass-fail scenarios, CRIMSON shows consistent agreement with expert judgment. In RadPref, a larger radiologist preference benchmark of over 100 pairwise cases with structured error categorization, severity modeling, and 1-5 overall quality ratings from three cardiothoracic radiologists, CRIMSON achieves the strongest alignment with radiologist preferences. We release the metric, the evaluation benchmarks, RadJudge and RadPref, and a fine-tuned MedGemma model to enable reproducible evaluation of report generation, all available at https://github.com/rajpurkarlab/CRIMSON.
