# CTForensics: A Comprehensive Dataset and Method for AI-Generated CT Image Detection

arXiv: https://arxiv.org/abs/2603.01878 · HTML: https://mlsanity.com/paper/2603.01878/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 29 of its 40 references that are in the map.
- First posted on arXiv 2 Mar 2026.

## Builds on (most cited first, 29 of 29)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Xception: Deep Learning with Depthwise Separable Convolutions](https://mlsanity.com/paper/1610.02357/) (2016)
- [EfficientNetV2: Smaller Models and Faster Training](https://mlsanity.com/paper/2104.00298/) (2021)
- [Leveraging Frequency Analysis for Deep Fake Image Recognition](https://mlsanity.com/paper/2003.08685/) (2020)
- [Towards Universal Fake Image Detectors that Generalize Across Generative Models](https://mlsanity.com/paper/2302.10174/) (2023)
- [Generalist Foundation Models from a Multimodal Dataset for 3D Computed Tomography](https://mlsanity.com/paper/2403.17834/) (2024)
- [Searching Central Difference Convolutional Networks for Face Anti-Spoofing](https://mlsanity.com/paper/2003.04092/) (2020)
- [Frequency-aware Discriminative Feature Learning Supervised by Single-Center Loss for Face Forgery Detection](https://mlsanity.com/paper/2103.09096/) (2021)
- [Improving Synthetic Image Detection Towards Generalization: An Image Transformation Perspective](https://mlsanity.com/paper/2408.06741/) (2024)
- [Wavelet Convolutions for Large Receptive Fields](https://mlsanity.com/paper/2407.05848/) (2024)
- [Conversion Between CT and MRI Images Using Diffusion and Score-Matching Models](https://mlsanity.com/paper/2209.12104/) (2022)
- [Anatomically-Controllable Medical Image Generation with Segmentation-Guided Diffusion Models](https://mlsanity.com/paper/2402.05210/) (2024)
- [GenerateCT: Text-Conditional Generation of 3D Chest CT Volumes](https://mlsanity.com/paper/2305.16037/) (2023)
- [Hierarchical Amortized Training for Memory-efficient High Resolution 3D GAN](https://mlsanity.com/paper/2008.01910/) (2020)
- [MedSyn: Text-guided Anatomy-aware Synthesis of High-Fidelity 3D CT Images](https://mlsanity.com/paper/2310.03559/) (2023)
- [CT-GAN: Malicious Tampering of 3D Medical Imagery using Deep Learning](https://mlsanity.com/paper/1901.03597/) (2019)
- [Generative Enhancement for 3D Medical Images](https://mlsanity.com/paper/2403.12852/) (2024)
- [FerretNet: Efficient Synthetic Image Detection via Local Pixel Dependencies](https://mlsanity.com/paper/2509.20890/) (2025)
- [CWNet: Causal Wavelet Network for Low-Light Image Enhancement](https://mlsanity.com/paper/2507.10689/) (2025)
- [Towards Generalizable AI-Generated Image Detection via Image-Adaptive Prompt Learning](https://mlsanity.com/paper/2508.01603/) (2025)
- [TRACE: Temporally Reliable Anatomically-Conditioned 3D CT Generation with Enhanced Efficiency](https://mlsanity.com/paper/2507.00802/) (2025)
- [Lung-DDPM: Semantic Layout-guided Diffusion Models for Thoracic CT Image Synthesis](https://mlsanity.com/paper/2502.15204/) (2025)
- [From Alignment to Synthesis: Contrastive Volumetric Grounding for Text-to-CT Generation](https://mlsanity.com/paper/2506.00633/) (2025)
- [Toward Medical Deepfake Detection: A Comprehensive Dataset and Novel Method](https://mlsanity.com/paper/2509.15711/) (2025)
- [Machine Learning based Medical Image Deepfake Detection: A Comparative Study](https://mlsanity.com/paper/2109.12800/) (2021)
- [Back-in-Time Diffusion: Unsupervised Detection of Medical Deepfakes](https://mlsanity.com/paper/2407.15169/) (2024)
- [Lung-DDPM+: Efficient Thoracic CT Image Synthesis using Diffusion Probabilistic Model](https://mlsanity.com/paper/2508.09327/) (2025)

## Abstract (arXiv)

Recent advances in generative AI have made synthetic Computed Tomography (CT) images increasingly realistic, enabling promising applications in medical data augmentation while raising serious concerns about clinical safety and data trustworthiness. Detecting AI-generated CT images remains challenging for two key reasons: existing benchmarks cover only limited generation sources, and many detectors are adapted from natural-image forensics without explicitly modeling CT-specific imaging properties. In this paper, we introduce CTForensics, a dataset for detecting AI-generated CT images. CTForensics contains 75,990 2D CT images, including a dedicated test benchmark of 29,990 balanced authentic and generated samples from ten representative CT generative models spanning GAN-based and diffusion-based paradigms. We further propose the Enhanced Spatial-Frequency CT Forgery Detector (ESF-CTFD), a CT-oriented CNN framework built around a Wavelet-Enhanced Central Stem, Multi-Scale Spatial Aggregation, and a Frequency-Aware Prediction Block. The Wavelet-Enhanced Central Stem enhances local intensity correlations and high-frequency residuals, Multi-Scale Spatial Aggregation aligns anatomical features across resolutions with lightweight residual units, and the Frequency-Aware Prediction Block models global spectral artifacts. Extensive experiments on CTForensics show that ESF-CTFD achieves 96.01% mAcc and 99.96% mAP, outperforming existing methods and maintaining strong robustness under realistic perturbations with only a 0.99% average drop. Codes will be available at https://github.com/liyih/CTForensics.