# Brain Tumor Segmentation with Special Emphasis on the Non-Enhancing Brain Tumor Compartment

arXiv: https://arxiv.org/abs/2602.21703 · HTML: https://mlsanity.com/paper/2602.21703/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 22 of its 80 references that are in the map.
- First posted on arXiv 25 Feb 2026.

## Builds on (most cited first, 22 of 22)

- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Fully Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1411.4038/) (2014)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [UNet++: Redesigning Skip Connections to Exploit Multiscale Features in Image Segmentation](https://mlsanity.com/paper/1912.05074/) (2019)
- [The RSNA-ASNR-MICCAI BraTS 2021 Benchmark on Brain Tumor Segmentation and Radiogenomic Classification](https://mlsanity.com/paper/2107.02314/) (2021)
- [Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challenge](https://mlsanity.com/paper/1811.02629/) (2018)
- [3D MRI brain tumor segmentation using autoencoder regularization](https://mlsanity.com/paper/1810.11654/) (2018)
- [Efficient Multi-Scale 3D CNN with Fully Connected CRF for Accurate Brain Lesion Segmentation](https://mlsanity.com/paper/1603.05959/) (2016)
- [Recurrent Residual Convolutional Neural Network based on U-Net (R2U-Net) for Medical Image Segmentation](https://mlsanity.com/paper/1802.06955/) (2018)
- [Brain Tumor Segmentation with Deep Neural Networks](https://mlsanity.com/paper/1505.03540/) (2015)
- [nnU-Net for Brain Tumor Segmentation](https://mlsanity.com/paper/2011.00848/) (2020)
- [TernausNet: U-Net with VGG11 Encoder Pre-Trained on ImageNet for Image Segmentation](https://mlsanity.com/paper/1801.05746/) (2018)
- [Common Limitations of Image Processing Metrics: A Picture Story](https://mlsanity.com/paper/2104.05642/) (2021)
- [Understanding metric-related pitfalls in image analysis validation](https://mlsanity.com/paper/2302.01790/) (2023)
- [Recent progress in semantic image segmentation](https://mlsanity.com/paper/1809.10198/) (2018)
- [Deep Learning Based Brain Tumor Segmentation: A Survey](https://mlsanity.com/paper/2007.09479/) (2020)
- [Effective and Efficient Dropout for Deep Convolutional Neural Networks](https://mlsanity.com/paper/1904.03392/) (2019)
- [A multi-scale pyramid of 3D fully convolutional networks for abdominal multi-organ segmentation](https://mlsanity.com/paper/1806.02237/) (2018)
- [Redundancy Reduction in Semantic Segmentation of 3D Brain Tumor MRIs](https://mlsanity.com/paper/2111.00742/) (2021)
- [Robust Semantic Segmentation of Brain Tumor Regions from 3D MRIs](https://mlsanity.com/paper/2001.02040/) (2020)

## Abstract (arXiv)

A U-Net based deep learning architecture is designed to segment brain tumors as they appear on various MRI modalities. Special emphasis is lent to the non-enhancing tumor compartment. The latter has not been considered anymore in recent brain tumor segmentation challenges like the MICCAI challenges. However, it is considered to be indicative of the survival time of the patient as well as of areas of further tumor growth. Hence it deems essential to have means to automatically delineate its extension within the tumor.