# "Are You Sure?": An Empirical Study of Human Perception Vulnerability in LLM-Driven Agentic Systems

arXiv: https://arxiv.org/abs/2602.21127 · HTML: https://mlsanity.com/paper/2602.21127/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Agent threats, guardrails and governance, one of 16 directions in LLM agents and tool use.
- Builds on 47 of its 106 references that are in the map.
- First posted on arXiv 24 Feb 2026.

## Placed in

- LLM agents and tool use / [Agent threats, guardrails and governance](https://mlsanity.com/agents/agent-threats-guardrails-and-governance/)

## Builds on (most cited first, 30 of 47)

- [ReAct: Synergizing Reasoning and Acting in Language Models](https://mlsanity.com/paper/2210.03629/) (2022)
- [A Survey on Large Language Model based Autonomous Agents](https://mlsanity.com/paper/2308.11432/) (2023)
- [MetaGPT: Meta Programming for A Multi-Agent Collaborative Framework](https://mlsanity.com/paper/2308.00352/) (2023)
- [Not what you've signed up for: Compromising Real-World LLM-Integrated Applications with Indirect Prompt Injection](https://mlsanity.com/paper/2302.12173/) (2023)
- [MemGPT: Towards LLMs as Operating Systems](https://mlsanity.com/paper/2310.08560/) (2023)
- [COMET: A Neural Framework for MT Evaluation](https://mlsanity.com/paper/2009.09025/) (2020)
- [ChatDev: Communicative Agents for Software Development](https://mlsanity.com/paper/2307.07924/) (2023)
- [A Survey on the Memory Mechanism of Large Language Model based Agents](https://mlsanity.com/paper/2404.13501/) (2024)
- [Prompt Injection attack against LLM-integrated Applications](https://mlsanity.com/paper/2306.05499/) (2023)
- [InjecAgent: Benchmarking Indirect Prompt Injections in Tool-Integrated Large Language Model Agents](https://mlsanity.com/paper/2403.02691/) (2024)
- [AgentPoison: Red-teaming LLM Agents via Poisoning Memory or Knowledge Bases](https://mlsanity.com/paper/2407.12784/) (2024)
- [PoisonedRAG: Knowledge Corruption Attacks to Retrieval-Augmented Generation of Large Language Models](https://mlsanity.com/paper/2402.07867/) (2024)
- [Large Language Model Agent: A Survey on Methodology, Applications and Challenges](https://mlsanity.com/paper/2503.21460/) (2025)
- [The Landscape of Emerging AI Agent Architectures for Reasoning, Planning, and Tool Calling: A Survey](https://mlsanity.com/paper/2404.11584/) (2024)
- [Prompt Injection Attack to Tool Selection in LLM Agents](https://mlsanity.com/paper/2504.19793/) (2025)
- [Agent Smith: A Single Image Can Jailbreak One Million Multimodal LLM Agents Exponentially Fast](https://mlsanity.com/paper/2402.08567/) (2024)
- [IsolateGPT: An Execution Isolation Architecture for LLM-Based Agentic Systems](https://mlsanity.com/paper/2403.04960/) (2024)
- [AI Agents Under Threat: A Survey of Key Security Challenges and Future Pathways](https://mlsanity.com/paper/2406.02630/) (2024)
- [Advances and Challenges in Foundation Agents: From Brain-Inspired Intelligence to Evolutionary, Collaborative, and Safe Systems](https://mlsanity.com/paper/2504.01990/) (2025)
- [Automatic and Universal Prompt Injection Attacks against Large Language Models](https://mlsanity.com/paper/2403.04957/) (2024)
- [WebPilot: A Versatile and Autonomous Multi-Agent System for Web Task Execution with Strategic Exploration](https://mlsanity.com/paper/2408.15978/) (2024)
- [A Survey on Trustworthy LLM Agents: Threats and Countermeasures](https://mlsanity.com/paper/2503.09648/) (2025)
- [PlanGenLLMs: A Modern Survey of LLM Planning Capabilities](https://mlsanity.com/paper/2502.11221/) (2025)
- [Imprompter: Tricking LLM Agents into Improper Tool Use](https://mlsanity.com/paper/2410.14923/) (2024)
- [A-MemGuard: A Proactive Defense Framework for LLM-Based Agent Memory](https://mlsanity.com/paper/2510.02373/) (2025)
- [Risk Taxonomy, Mitigation, and Assessment Benchmarks of Large Language Model Systems](https://mlsanity.com/paper/2401.05778/) (2024)
- [Navigating the Risks: A Survey of Security, Privacy, and Ethics Threats in LLM-Based Agents](https://mlsanity.com/paper/2411.09523/) (2024)
- ["It's a Fair Game", or Is It? Examining How Users Navigate Disclosure Risks and Benefits When Using LLM-Based Conversational Agents](https://mlsanity.com/paper/2309.11653/) (2023)
- [The Obvious Invisible Threat: LLM-Powered GUI Agents' Vulnerability to Fine-Print Injections](https://mlsanity.com/paper/2504.11281/) (2025)
- [Are We There Yet? Revealing the Risks of Utilizing Large Language Models in Scholarly Peer Review](https://mlsanity.com/paper/2412.01708/) (2024)

## Abstract (arXiv)

Large language model (LLM) agents are rapidly becoming trusted copilots in high-stakes domains like software development and healthcare. However, this deepening trust introduces a novel attack surface: Agent-Mediated Deception (AMD), where compromised agents are weaponized against their human users. While extensive research focuses on agent-centric threats, human susceptibility to deception by a compromised agent remains unexplored. We present the first large-scale empirical study with 303 participants to measure human susceptibility to AMD. This is based on HAT-Lab (Human-Agent Trust Laboratory), a high-fidelity research platform we develop, featuring nine carefully crafted scenarios spanning everyday and professional domains (e.g., healthcare, software development, human resources). Our 10 key findings reveal significant vulnerabilities and provide future defense perspectives. Specifically, only 8.6% of participants perceive AMD attacks, while domain experts show increased susceptibility in certain scenarios. We identify six cognitive failure modes in users and find that their risk awareness often fails to translate to protective behavior. The defense analysis reveals that effective warnings should interrupt workflows with low verification costs. With experiential learning based on HAT-Lab, over 90% of users who perceive risks report increased caution against AMD. This work provides empirical evidence and a platform for human-centric agent security research.