# DataJoint 2.0: A Computational Substrate for Agentic Scientific Workflows

arXiv: https://arxiv.org/abs/2602.16585 · HTML: https://mlsanity.com/paper/2602.16585/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Web, search, and research agents, one of 16 directions in LLM agents and tool use.
- Builds on 3 of its 37 references that are in the map.
- First posted on arXiv 18 Feb 2026.

## Placed in

- LLM agents and tool use / [Web, search, and research agents](https://mlsanity.com/agents/web-search-and-research-agents/)

## Builds on (most cited first, 3 of 3)

- [Markerless Motion Capture and Biomechanical Analysis Pipeline](https://mlsanity.com/paper/2303.10654/) (2023)
- [Calibrated Uncertainty for Trustworthy Clinical Gait Analysis Using Probabilistic Multiview Markerless Motion Capture](https://mlsanity.com/paper/2601.22412/) (2026)
- [SciOps: Achieving Productivity and Reliability in Data-Intensive Research](https://mlsanity.com/paper/2401.00077/) (2023)

## Abstract (arXiv)

Operational rigor determines whether human-agent collaboration succeeds or fails. Scientific data pipelines need the equivalent of DevOps -- SciOps -- yet common approaches fragment provenance across disconnected systems without transactional guarantees. DataJoint 2.0 addresses this gap through the relational workflow model: tables represent workflow steps, rows represent artifacts, foreign keys prescribe execution order. The schema specifies not only what data exists but how it is derived -- a single formal system where data structure, computational dependencies, and integrity constraints are all queryable, enforceable, and machine-readable. Four technical innovations extend this foundation: object-augmented schemas integrating relational metadata with scalable object storage, semantic matching using attribute lineage to prevent erroneous joins, an extensible type system for domain-specific formats, and distributed job coordination designed for composability with external orchestration. By unifying data structure, data, and computational transformations, DataJoint creates a substrate for SciOps where agents can participate in scientific workflows without risking data corruption.