# OmniCT: Towards a Unified Slice-Volume LVLM for Comprehensive CT Analysis

arXiv: https://arxiv.org/abs/2602.16110 · HTML: https://mlsanity.com/paper/2602.16110/

## Key facts

- Cited by 10 papers in the map (data through 14 Oct 2026).
- Builds on 57 of its 77 references that are in the map.
- First posted on arXiv 18 Feb 2026.

## Builds on (most cited first, 30 of 57)

- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Qwen3 Technical Report](https://mlsanity.com/paper/2505.09388/) (2025)
- [Qwen2.5-VL Technical Report](https://mlsanity.com/paper/2502.13923/) (2025)
- [BERTScore: Evaluating Text Generation with BERT](https://mlsanity.com/paper/1904.09675/) (2019)
- [Sigmoid Loss for Language Image Pre-Training](https://mlsanity.com/paper/2303.15343/) (2023)
- [Qwen3-VL Technical Report](https://mlsanity.com/paper/2511.21631/) (2025)
- [LLaVA-OneVision: Easy Visual Task Transfer](https://mlsanity.com/paper/2408.03326/) (2024)
- [Wan: Open and Advanced Large-Scale Video Generative Models](https://mlsanity.com/paper/2503.20314/) (2025)
- [Qwen2 Technical Report](https://mlsanity.com/paper/2407.10671/) (2024)
- [InternVL3: Exploring Advanced Training and Test-Time Recipes for Open-Source Multimodal Models](https://mlsanity.com/paper/2504.10479/) (2025)
- [Gemma 3 Technical Report](https://mlsanity.com/paper/2503.19786/) (2025)
- [DINOv3](https://mlsanity.com/paper/2508.10104/) (2025)
- [Video-MME: The First-Ever Comprehensive Evaluation Benchmark of Multi-modal LLMs in Video Analysis](https://mlsanity.com/paper/2405.21075/) (2024)
- [Video-LLaVA: Learning United Visual Representation by Alignment Before Projection](https://mlsanity.com/paper/2311.10122/) (2023)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [Qwen3 Embedding: Advancing Text Embedding and Reranking Through Foundation Models](https://mlsanity.com/paper/2506.05176/) (2025)
- [TotalSegmentator: robust segmentation of 104 anatomical structures in CT images](https://mlsanity.com/paper/2208.05868/) (2022)
- [LLaMA-VID: An Image is Worth 2 Tokens in Large Language Models](https://mlsanity.com/paper/2311.17043/) (2023)
- [VideoMAE V2: Scaling Video Masked Autoencoders with Dual Masking](https://mlsanity.com/paper/2303.16727/) (2023)
- [Phi-4-Mini Technical Report: Compact yet Powerful Multimodal Language Models via Mixture-of-LoRAs](https://mlsanity.com/paper/2503.01743/) (2025)
- [BiomedCLIP: a multimodal biomedical foundation model pretrained from fifteen million scientific image-text pairs](https://mlsanity.com/paper/2303.00915/) (2023)
- [VideoLLaMA 3: Frontier Multimodal Foundation Models for Image and Video Understanding](https://mlsanity.com/paper/2501.13106/) (2025)
- [MMMU-Pro: A More Robust Multi-discipline Multimodal Understanding Benchmark](https://mlsanity.com/paper/2409.02813/) (2024)
- [SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answering](https://mlsanity.com/paper/2102.09542/) (2021)
- [MedGemma Technical Report](https://mlsanity.com/paper/2507.05201/) (2025)
- [HealthBench: Evaluating Large Language Models Towards Improved Human Health](https://mlsanity.com/paper/2505.08775/) (2025)
- [Med-Flamingo: a Multimodal Medical Few-shot Learner](https://mlsanity.com/paper/2307.15189/) (2023)
- [PLLaVA : Parameter-free LLaVA Extension from Images to Videos for Video Dense Captioning](https://mlsanity.com/paper/2404.16994/) (2024)
- [Capabilities of Gemini Models in Medicine](https://mlsanity.com/paper/2404.18416/) (2024)
- [Lingshu: A Generalist Foundation Model for Unified Multimodal Medical Understanding and Reasoning](https://mlsanity.com/paper/2506.07044/) (2025)

## Built on by (most cited first, 10 of 10)

- [InstructSAM: Segment Any Instance with Any Instructions](https://mlsanity.com/paper/2605.26102/) (2026)
- [E-MRL: Cross-view Aligned Evidence-driven Multimodal Reinforcement Learning for Reliable 3D Tumor Analysis](https://mlsanity.com/paper/2606.23888/) (2026)
- [Regulating Anatomy-Aware Rewards via Trajectory-Integral Feedback for Volumetric Computed Tomography Analysis](https://mlsanity.com/paper/2605.20277/) (2026)
- [CT-Flow: Orchestrating CT Interpretation Workflow with Model Context Protocol Servers](https://mlsanity.com/paper/2603.00123/) (2026)
- [RadSight: Towards Perceptually Reliable Multimodal Radiology Image Understanding](https://mlsanity.com/paper/2607.22293/) (2026)
- [HounsWorld: A Multimodal World Model for Hidden Patient-State Readout, Reconstruction, and Simulation](https://mlsanity.com/paper/2608.12904/) (2026)
- [Holtercare-Bench: A Multimodal Benchmark for Evaluating Long-Term Dynamic ECG Analysis](https://mlsanity.com/paper/2608.19297/) (2026)
- [Volumetric Radiology AI in the Era of Multimodal Large Language Models](https://mlsanity.com/paper/2608.20549/) (2026)
- [SeVeR: Selective Visual Exposure and Retrieval for 3D Medical Image Question Answering](https://mlsanity.com/paper/2608.25630/) (2026)
- [SelfCue: Making a 3D CT Report Generator Say What It Already Knows](https://mlsanity.com/paper/2609.31788/) (2026)

## Abstract (arXiv)

Computed Tomography (CT) is one of the most widely used and diagnostically information-dense imaging modalities, covering critical organs such as the heart, lungs, liver, and colon. Clinical interpretation relies on both slice-driven local features (e.g., sub-centimeter nodules, lesion boundaries) and volume-driven spatial representations (e.g., tumor infiltration, inter-organ anatomical relations). However, existing Large Vision-Language Models (LVLMs) remain fragmented in CT slice versus volumetric understanding: slice-driven LVLMs show strong generalization but lack cross-slice spatial consistency, while volume-driven LVLMs explicitly capture volumetric semantics but suffer from coarse granularity and poor compatibility with slice inputs. The absence of a unified modeling paradigm constitutes a major bottleneck for the clinical translation of medical LVLMs. We present OmniCT, a powerful unified slice-volume LVLM for CT scenarios, which makes three contributions: (i) Spatial Consistency Enhancement (SCE): volumetric slice composition combined with tri-axial positional embedding that introduces volumetric consistency, and an MoE hybrid projection enables efficient slice-volume adaptation; (ii) Organ-level Semantic Enhancement (OSE): segmentation and ROI localization explicitly align anatomical regions, emphasizing lesion- and organ-level semantics; (iii) MedEval-CT: the largest slice-volume CT dataset and hybrid benchmark integrates comprehensive metrics for unified evaluation. OmniCT consistently outperforms existing methods with a substantial margin across diverse clinical tasks and satisfies both micro-level detail sensitivity and macro-level spatial reasoning. More importantly, it establishes a new paradigm for cross-modal medical imaging understanding. Our project is available at https://github.com/ZJU4HealthCare/OmniCT.