# MELINOE: Fine-Tuning Enables Memory-Efficient Inference for Mixture-of-Experts Models

arXiv: https://arxiv.org/abs/2602.11192 · HTML: https://mlsanity.com/paper/2602.11192/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Placed in Efficient MoE training and inference systems, one of 12 directions in Mixture-of-experts.
- Builds on 16 of its 39 references that are in the map.
- First posted on arXiv 30 Jan 2026.

## Placed in

- Mixture-of-experts / [Efficient MoE training and inference systems](https://mlsanity.com/moe/efficient-moe-training-and-inference-systems/)

## Builds on (most cited first, 16 of 16)

- [Training Verifiers to Solve Math Word Problems](https://mlsanity.com/paper/2110.14168/) (2021)
- [Qwen2 Technical Report](https://mlsanity.com/paper/2407.10671/) (2024)
- [Phi-3 Technical Report: A Highly Capable Language Model Locally on Your Phone](https://mlsanity.com/paper/2404.14219/) (2024)
- [Mixtral of Experts](https://mlsanity.com/paper/2401.04088/) (2024)
- [DeepSeek-V2: A Strong, Economical, and Efficient Mixture-of-Experts Language Model](https://mlsanity.com/paper/2405.04434/) (2024)
- [DeepSeek-V3 Technical Report](https://mlsanity.com/paper/2412.19437/) (2024)
- [Auxiliary-Loss-Free Load Balancing Strategy for Mixture-of-Experts](https://mlsanity.com/paper/2408.15664/) (2024)
- [Fast Inference of Mixture-of-Experts Language Models with Offloading](https://mlsanity.com/paper/2312.17238/) (2023)
- [MoE-Infinity: Efficient MoE Inference on Personal Machines with Sparsity-Aware Expert Cache](https://mlsanity.com/paper/2401.14361/) (2024)
- [Taming Latency-Memory Trade-Off in MoE-Based LLM Serving via Fine-Grained Expert Offloading](https://mlsanity.com/paper/2502.05370/) (2025)
- [Finding Fantastic Experts in MoEs: A Unified Study for Expert Dropping Strategies and Observations](https://mlsanity.com/paper/2504.05586/) (2025)
- [Faster MoE LLM Inference for Extremely Large Models](https://mlsanity.com/paper/2505.03531/) (2025)
- [Not All Models Suit Expert Offloading: On Local Routing Consistency of Mixture-of-Expert Models](https://mlsanity.com/paper/2505.16056/) (2025)
- [HarMoEny: Efficient Multi-GPU Inference of MoE Models](https://mlsanity.com/paper/2506.12417/) (2025)
- [BlockFFN: Towards End-Side Acceleration-Friendly Mixture-of-Experts with Chunk-Level Activation Sparsity](https://mlsanity.com/paper/2507.08771/) (2025)
- [BuddyMoE: Exploiting Expert Redundancy to Accelerate Memory-Constrained Mixture-of-Experts Inference](https://mlsanity.com/paper/2511.10054/) (2025)

## Built on by (most cited first, 2 of 2)

- [Cacheable by Design? Training Mixture-of-Experts Routers for Locality Against the Edge Memory-Bandwidth Wall: A Pre-Registered Negative Result with a Systems Measurement Study](https://mlsanity.com/paper/2608.18261/) (2026)
- [FluxMoE: Decoupling Expert Residency for High-Performance MoE Serving](https://mlsanity.com/paper/2604.02715/) (2026)

## Abstract (arXiv)

Mixture-of-Experts (MoE) model architectures can significantly reduce the number of activated parameters per token, enabling computationally efficient training and inference. However, their large overall parameter counts and model sizes have precluded their widespread usage in resource-constrained settings as all of the parameters must still be loaded into GPU memory. Prior works aim to address this memory bottleneck by offloading certain experts into CPU memory and porting them to GPU memory only when they are activated. In practice, these methods suffer from the significant I/O latency incurred by expert transfer. We present MELINOE, a method that fine-tunes an MoE model to more strongly prefer activating a smaller number of experts per sequence. Caching these preferred experts in GPU memory reduces expert churn and CPU-GPU transfer overhead. MELINOE increases throughput by 1.2-3× over efficient baselines and up to 14.7× over transfer-heavy baselines while retaining or even improving the performance of the model on a downstream task, making it a reliable method for improving MoE inference efficiency.