# Generalized Prediction-Powered Inference, with Application to Binary Classifier Evaluation

arXiv: https://arxiv.org/abs/2602.10332 · HTML: https://mlsanity.com/paper/2602.10332/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 13 of its 30 references that are in the map.
- First posted on arXiv 10 Feb 2026.

## Builds on (most cited first, 13 of 13)

- [Prediction-Powered Inference](https://mlsanity.com/paper/2301.09633/) (2023)
- [PPI++: Efficient Prediction-Powered Inference](https://mlsanity.com/paper/2311.01453/) (2023)
- [Cross-Prediction-Powered Inference](https://mlsanity.com/paper/2309.16598/) (2023)
- [Active Statistical Inference](https://mlsanity.com/paper/2403.03208/) (2024)
- [Using simulation studies to evaluate statistical methods](https://mlsanity.com/paper/1712.03198/) (2017)
- [Assumption-Lean and Data-Adaptive Post-Prediction Inference](https://mlsanity.com/paper/2311.14220/) (2023)
- [Extending inferences from a randomized trial to a new target population](https://mlsanity.com/paper/1805.00550/) (2018)
- [Prediction-Powered Inference with Imputed Covariates and Nonuniform Sampling](https://mlsanity.com/paper/2501.18577/) (2025)
- [Prediction De-Correlated Inference: A safe approach for post-prediction inference](https://mlsanity.com/paper/2312.06478/) (2023)
- [A Unified Framework for Semiparametrically Efficient Semi-Supervised Learning](https://mlsanity.com/paper/2502.17741/) (2025)
- [Task-Agnostic Machine-Learning-Assisted Inference](https://mlsanity.com/paper/2405.20039/) (2024)
- [Efficient nonparametric inference on the effects of stochastic interventions under two-phase sampling, with applications to vaccine efficacy trials](https://mlsanity.com/paper/2003.13771/) (2020)
- [Entropy Balancing for Causal Generalization with Target Sample Summary Information](https://mlsanity.com/paper/2201.08012/) (2022)

## Built on by (most cited first, 3 of 3)

- [When Can You Trust Your Synthetic Users? Diagnostics and Corrections for LLM Consumer Panels](https://mlsanity.com/paper/2609.13148/) (2026)
- [Optimal Inference with Black-box Predictions](https://mlsanity.com/paper/2608.10155/) (2026)
- [How to Run Statistics over LLM Judges and Trust the Results: Calibrated Inference for Small-Sample AI Evaluation with evalstats](https://mlsanity.com/paper/2609.35815/) (2026)

## Abstract (arXiv)

In the partially-observed outcome setting, a recent set of proposals known as "prediction-powered inference" (PPI) involve (i) applying a pre-trained machine learning model to predict the response, and then (ii) using these predictions to obtain an estimator of the parameter of interest with asymptotic variance no greater than that which would be obtained using only the labeled observations. While existing PPI proposals consider estimators arising from M-estimation, in this paper we generalize PPI to any regular asymptotically linear estimator. Furthermore, by situating PPI within the context of an existing rich literature on missing data and semi-parametric efficiency theory, we show that while PPI does not achieve the semi-parametric efficiency lower bound outside of very restrictive and unrealistic scenarios, it can be viewed as a computationally-simple alternative to proposals in that literature. We exploit connections to that literature to propose modified PPI estimators that can handle three distinct forms of covariate distribution shift. Finally, we illustrate these developments by constructing PPI estimators of true positive rate, false positive rate, and area under the curve via numerical studies.
