# Agentic AI in Healthcare & Medicine: A Seven-Dimensional Taxonomy for Empirical Evaluation of LLM-based Agents

arXiv: https://arxiv.org/abs/2602.04813 · HTML: https://mlsanity.com/paper/2602.04813/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use.
- Builds on 109 of its 145 references that are in the map.
- First posted on arXiv 4 Feb 2026.

## Placed in

- LLM agents and tool use / [Medical and scientific domain agents](https://mlsanity.com/agents/medical-and-scientific-domain-agents/)

## Builds on (most cited first, 30 of 109)

- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [ReAct: Synergizing Reasoning and Acting in Language Models](https://mlsanity.com/paper/2210.03629/) (2022)
- [Self-Consistency Improves Chain of Thought Reasoning in Language Models](https://mlsanity.com/paper/2203.11171/) (2022)
- [PaLM: Scaling Language Modeling with Pathways](https://mlsanity.com/paper/2204.02311/) (2022)
- [Model-Agnostic Meta-Learning for Fast Adaptation of Deep Networks](https://mlsanity.com/paper/1703.03400/) (2017)
- [Flamingo: a Visual Language Model for Few-Shot Learning](https://mlsanity.com/paper/2204.14198/) (2022)
- [Reflexion: Language Agents with Verbal Reinforcement Learning](https://mlsanity.com/paper/2303.11366/) (2023)
- [Toolformer: Language Models Can Teach Themselves to Use Tools](https://mlsanity.com/paper/2302.04761/) (2023)
- [Tree of Thoughts: Deliberate Problem Solving with Large Language Models](https://mlsanity.com/paper/2305.10601/) (2023)
- [Constitutional AI: Harmlessness from AI Feedback](https://mlsanity.com/paper/2212.08073/) (2022)
- [REALM: Retrieval-Augmented Language Model Pre-Training](https://mlsanity.com/paper/2002.08909/) (2020)
- [AutoGen: Enabling Next-Gen LLM Applications via Multi-Agent Conversation](https://mlsanity.com/paper/2308.08155/) (2023)
- [Self-RAG: Learning to Retrieve, Generate, and Critique through Self-Reflection](https://mlsanity.com/paper/2310.11511/) (2023)
- [Large Language Models Encode Clinical Knowledge](https://mlsanity.com/paper/2212.13138/) (2022)
- [The Rise and Potential of Large Language Model Based Agents: A Survey](https://mlsanity.com/paper/2309.07864/) (2023)
- [Jailbreaking Black Box Large Language Models in Twenty Queries](https://mlsanity.com/paper/2310.08419/) (2023)
- [MemGPT: Towards LLMs as Operating Systems](https://mlsanity.com/paper/2310.08560/) (2023)
- [Mass-Editing Memory in a Transformer](https://mlsanity.com/paper/2210.07229/) (2022)
- [SelfCheckGPT: Zero-Resource Black-Box Hallucination Detection for Generative Large Language Models](https://mlsanity.com/paper/2303.08896/) (2023)
- [Generalization through Memorization: Nearest Neighbor Language Models](https://mlsanity.com/paper/1911.00172/) (2019)
- [Large Language Model based Multi-Agents: A Survey of Progress and Challenges](https://mlsanity.com/paper/2402.01680/) (2024)
- [Bias and Fairness in Large Language Models: A Survey](https://mlsanity.com/paper/2309.00770/) (2023)
- [Capabilities of GPT-4 on Medical Challenge Problems](https://mlsanity.com/paper/2303.13375/) (2023)
- [A Survey on the Memory Mechanism of Large Language Model based Agents](https://mlsanity.com/paper/2404.13501/) (2024)
- [The Future of Digital Health with Federated Learning](https://mlsanity.com/paper/2003.08119/) (2020)
- [ChemCrow: Augmenting large-language models with chemistry tools](https://mlsanity.com/paper/2304.05376/) (2023)
- [Plan-and-Solve Prompting: Improving Zero-Shot Chain-of-Thought Reasoning by Large Language Models](https://mlsanity.com/paper/2305.04091/) (2023)

## Built on by (most cited first, 1 of 1)

- [Agentic AI in medicine: architectures, applications, evaluation, and challenges for clinical translation](https://mlsanity.com/paper/2607.25489/) (2026)

## Abstract (arXiv)

Large Language Model (LLM)-based agents that plan, use tools and act has begun to shape healthcare and medicine. Reported studies demonstrate competence on various tasks ranging from EHR analysis and differential diagnosis to treatment planning and research workflows. Yet the literature largely consists of overviews which are either broad surveys or narrow dives into a single capability (e.g., memory, planning, reasoning), leaving healthcare work without a common frame. We address this by reviewing 49 studies using a seven-dimensional taxonomy: Cognitive Capabilities, Knowledge Management, Interaction Patterns, Adaptation & Learning, Safety & Ethics, Framework Typology and Core Tasks & Subtasks with 29 operational sub-dimensions. Using explicit inclusion and exclusion criteria and a labeling rubric (Fully Implemented, Partially Implemented, Not Implemented), we map each study to the taxonomy and report quantitative summaries of capability prevalence and co-occurrence patterns. Our empirical analysis surfaces clear asymmetries. For instance, the External Knowledge Integration sub-dimension under Knowledge Management is commonly realized (~76% Fully Implemented) whereas Event-Triggered Activation sub-dimenison under Interaction Patterns is largely absent (~92% Not Implemented) and Drift Detection & Mitigation sub-dimension under Adaptation & Learning is rare (~98% Not Implemented). Architecturally, Multi-Agent Design sub-dimension under Framework Typology is the dominant pattern (~82% Fully Implemented) while orchestration layers remain mostly partial. Across Core Tasks & Subtasks, information centric capabilities lead e.g., Medical Question Answering & Decision Support and Benchmarking & Simulation, while action and discovery oriented areas such as Treatment Planning & Prescription still show substantial gaps (~59% Not Implemented).