# Modular Expert Merging for Biomedical Retrieval

arXiv: https://arxiv.org/abs/2602.04731 · HTML: https://mlsanity.com/paper/2602.04731/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 47 of its 69 references that are in the map.
- First posted on arXiv 4 Feb 2026.

## Builds on (most cited first, 30 of 47)

- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Representation Learning with Contrastive Predictive Coding](https://mlsanity.com/paper/1807.03748/) (2018)
- [Scaling Laws for Neural Language Models](https://mlsanity.com/paper/2001.08361/) (2020)
- [Dense Passage Retrieval for Open-Domain Question Answering](https://mlsanity.com/paper/2004.04906/) (2020)
- [SimCSE: Simple Contrastive Learning of Sentence Embeddings](https://mlsanity.com/paper/2104.08821/) (2021)
- [A large annotated corpus for learning natural language inference](https://mlsanity.com/paper/1508.05326/) (2015)
- [MS MARCO: A Human Generated MAchine Reading COmprehension Dataset](https://mlsanity.com/paper/1611.09268/) (2016)
- [Model soups: averaging weights of multiple fine-tuned models improves accuracy without increasing inference time](https://mlsanity.com/paper/2203.05482/) (2022)
- [FEVER: a large-scale dataset for Fact Extraction and VERification](https://mlsanity.com/paper/1803.05355/) (2018)
- [Qwen3 Embedding: Advancing Text Embedding and Reranking Through Foundation Models](https://mlsanity.com/paper/2506.05176/) (2025)
- [BEIR: A Heterogenous Benchmark for Zero-shot Evaluation of Information Retrieval Models](https://mlsanity.com/paper/2104.08663/) (2021)
- [Unsupervised Dense Information Retrieval with Contrastive Learning](https://mlsanity.com/paper/2112.09118/) (2021)
- [Approximate Nearest Neighbor Negative Contrastive Learning for Dense Text Retrieval](https://mlsanity.com/paper/2007.00808/) (2020)
- [TIES-Merging: Resolving Interference When Merging Models](https://mlsanity.com/paper/2306.01708/) (2023)
- [Language Models are Super Mario: Absorbing Abilities from Homologous Models as a Free Lunch](https://mlsanity.com/paper/2311.03099/) (2023)
- [Linear Mode Connectivity and the Lottery Ticket Hypothesis](https://mlsanity.com/paper/1912.05671/) (2019)
- [ELI5: Long Form Question Answering](https://mlsanity.com/paper/1907.09190/) (2019)
- [Fact or Fiction: Verifying Scientific Claims](https://mlsanity.com/paper/2004.14974/) (2020)
- [NV-Embed: Improved Techniques for Training LLMs as Generalist Embedding Models](https://mlsanity.com/paper/2405.17428/) (2024)
- [Large Dual Encoders Are Generalizable Retrievers](https://mlsanity.com/paper/2112.07899/) (2021)
- [SPECTER: Document-level Representation Learning using Citation-informed Transformers](https://mlsanity.com/paper/2004.07180/) (2020)
- [LLM2Vec: Large Language Models Are Secretly Powerful Text Encoders](https://mlsanity.com/paper/2404.05961/) (2024)
- [Benchmarking Retrieval-Augmented Generation for Medicine](https://mlsanity.com/paper/2402.13178/) (2024)
- [ChatDoctor: A Medical Chat Model Fine-Tuned on a Large Language Model Meta-AI (LLaMA) Using Medical Domain Knowledge](https://mlsanity.com/paper/2303.14070/) (2023)
- [BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains](https://mlsanity.com/paper/2402.10373/) (2024)
- [Evolutionary Optimization of Model Merging Recipes](https://mlsanity.com/paper/2403.13187/) (2024)
- [Arcee's MergeKit: A Toolkit for Merging Large Language Models](https://mlsanity.com/paper/2403.13257/) (2024)
- [Optimizing Dense Retrieval Model Training with Hard Negatives](https://mlsanity.com/paper/2104.08051/) (2021)
- [Linear Mode Connectivity in Multitask and Continual Learning](https://mlsanity.com/paper/2010.04495/) (2020)

## Abstract (arXiv)

Adapting general-purpose LLMs into domain-specialized dense retrievers typically requires large-scale training on mixed-domain data. We show that merging independently trained domain-specialized experts consistently exceeds this approach across four decoder-only LLM families (0.6B-7B), four merging methods, and twelve medical and general retrieval tasks from MTEB, suggesting that parameter-space composition captures complementary domain strengths that large-scale mixed-domain training averages out. To further maximize expert quality, we introduce Synthesize-Train-Merge (STM), a modular framework that synthesizes hard negatives with a top-tier LLM and fine-tunes domain-specialized experts via LoRA before merging them, without continual pre-training. Synthesized hard negatives yield the largest gains for smaller models, and STM achieves strong performance on biomedical retrieval tasks while maintaining competitive general-domain results across all four backbone families.