# Physiology as Language: Translating Respiration to Sleep EEG

arXiv: https://arxiv.org/abs/2602.00526 · HTML: https://mlsanity.com/paper/2602.00526/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 17 of its 40 references that are in the map.
- First posted on arXiv 31 Jan 2026.

## Builds on (most cited first, 17 of 17)

- [BART: Denoising Sequence-to-Sequence Pre-training for Natural Language Generation, Translation, and Comprehension](https://mlsanity.com/paper/1910.13461/) (2019)
- [Taming Transformers for High-Resolution Image Synthesis](https://mlsanity.com/paper/2012.09841/) (2020)
- [MaskGIT: Masked Generative Image Transformer](https://mlsanity.com/paper/2202.04200/) (2022)
- [MASS: Masked Sequence to Sequence Pre-training for Language Generation](https://mlsanity.com/paper/1905.02450/) (2019)
- [MAGE: MAsked Generative Encoder to Unify Representation Learning and Image Synthesis](https://mlsanity.com/paper/2211.09117/) (2022)
- [Fluid: Scaling Autoregressive Text-to-image Generative Models with Continuous Tokens](https://mlsanity.com/paper/2410.13863/) (2024)
- [Large-scale Training of Foundation Models for Wearable Biosignals](https://mlsanity.com/paper/2312.05409/) (2023)
- [SensorLM: Learning the Language of Wearable Sensors](https://mlsanity.com/paper/2506.09108/) (2025)
- [Neural network an1alysis of sleep stages enables efficient diagnosis of narcolepsy](https://mlsanity.com/paper/1710.02094/) (2017)
- [CardioGAN: Attentive Generative Adversarial Network with Dual Discriminators for Synthesis of ECG from PPG](https://mlsanity.com/paper/2010.00104/) (2020)
- [CroSSL: Cross-modal Self-Supervised Learning for Time-series through Latent Masking](https://mlsanity.com/paper/2307.16847/) (2023)
- [PPG2ABP: Translating Photoplethysmogram (PPG) Signals to Arterial Blood Pressure (ABP) Waveforms using Fully Convolutional Neural Networks](https://mlsanity.com/paper/2005.01669/) (2020)
- [Performer: A Novel PPG-to-ECG Reconstruction Transformer for a Digital Biomarker of Cardiovascular Disease Detection](https://mlsanity.com/paper/2204.11795/) (2022)
- [Promoting cross-modal representations to improve multimodal foundation models for physiological signals](https://mlsanity.com/paper/2410.16424/) (2024)
- [Pi-ViMo: Physiology-inspired Robust Vital Sign Monitoring using mmWave Radars](https://mlsanity.com/paper/2303.13816/) (2023)
- [What Radio Waves Tell Us about Sleep](https://mlsanity.com/paper/2405.11739/) (2024)
- [NT-ViT: Neural Transcoding Vision Transformers for EEG-to-fMRI Synthesis](https://mlsanity.com/paper/2409.11836/) (2024)

## Abstract (arXiv)

This paper introduces a novel cross-physiology translation task: synthesizing sleep electroencephalography (EEG) from respiration signals. To address the significant complexity gap between the two modalities, we propose a waveform-conditional generative framework that preserves fine-grained respiratory dynamics while constraining the EEG target space through discrete tokenization. Trained on over 28,000 individuals, our model achieves a 7% Mean Absolute Error in EEG spectrogram reconstruction. Beyond reconstruction, the synthesized EEG supports downstream tasks with performance comparable to ground truth EEG on age estimation (MAE 5.0 vs. 5.1 years), sex detection (AUROC 0.81 vs. 0.82), and sleep staging (Accuracy 0.84 vs. 0.88), significantly outperforming baselines trained directly on breathing. Finally, we demonstrate that the framework generalizes to contactless sensing by synthesizing EEG from wireless radio-frequency reflections, highlighting the feasibility of remote, non-contact neurological assessment during sleep.
