# Intelligent Reasoning Cues: A Framework and Case Study of the Roles of AI Information in Complex Decisions

arXiv: https://arxiv.org/abs/2602.00259 · HTML: https://mlsanity.com/paper/2602.00259/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 26 of its 95 references that are in the map.
- First posted on arXiv 30 Jan 2026.

## Builds on (most cited first, 26 of 26)

- [A Unified Approach to Interpreting Model Predictions](https://mlsanity.com/paper/1705.07874/) (2017)
- [Explaining Machine Learning Classifiers through Diverse Counterfactual Explanations](https://mlsanity.com/paper/1905.07697/) (2019)
- [Does the Whole Exceed its Parts? The Effect of AI Explanations on Complementary Team Performance](https://mlsanity.com/paper/2006.14779/) (2020)
- [When combinations of humans and AI are useful: A systematic review and meta-analysis](https://mlsanity.com/paper/2405.06087/) (2024)
- [Towards a Science of Human-AI Decision Making: A Survey of Empirical Studies](https://mlsanity.com/paper/2112.11471/) (2021)
- [Appropriate Reliance on AI Advice: Conceptualization and the Effect of Explanations](https://mlsanity.com/paper/2302.02187/) (2023)
- [Understanding the Role of Human Intuition on Reliance in Human-AI Decision-Making with Explanations](https://mlsanity.com/paper/2301.07255/) (2023)
- [Unremarkable AI: Fitting Intelligent Decision Support into Critical, Clinical Decision-Making Processes](https://mlsanity.com/paper/1904.09612/) (2019)
- ["The Human Body is a Black Box": Supporting Clinical Decision-Making with Deep Learning](https://mlsanity.com/paper/1911.08089/) (2019)
- [Improving Human-AI Partnerships in Child Welfare: Understanding Worker Practices, Challenges, and Desires for Algorithmic Decision Support](https://mlsanity.com/paper/2204.02310/) (2022)
- [Towards Human-AI Deliberation: Design and Evaluation of LLM-Empowered Deliberative AI for AI-Assisted Decision-Making](https://mlsanity.com/paper/2403.16812/) (2024)
- [Ignore, Trust, or Negotiate: Understanding Clinician Acceptance of AI-Based Treatment Recommendations in Health Care](https://mlsanity.com/paper/2302.00096/) (2023)
- [Improving Human-AI Collaboration With Descriptions of AI Behavior](https://mlsanity.com/paper/2301.06937/) (2023)
- [Improving Sepsis Treatment Strategies by Combining Deep and Kernel-Based Reinforcement Learning](https://mlsanity.com/paper/1901.04670/) (2019)
- [Rethinking Human-AI Collaboration in Complex Medical Decision Making: A Case Study in Sepsis Diagnosis](https://mlsanity.com/paper/2309.12368/) (2023)
- [Sibyl: Understanding and Addressing the Usability Challenges of Machine Learning In High-Stakes Decision Making](https://mlsanity.com/paper/2103.02071/) (2021)
- [Human-AI collaboration is not very collaborative yet: A taxonomy of interaction patterns in AI-assisted decision making from a systematic review](https://mlsanity.com/paper/2310.19778/) (2023)
- [Unifying Cardiovascular Modelling with Deep Reinforcement Learning for Uncertainty Aware Control of Sepsis Treatment](https://mlsanity.com/paper/2101.08477/) (2021)
- [Artificial Intelligence Should Genuinely Support Clinical Reasoning and Decision Making To Bridge the Translational Gap](https://mlsanity.com/paper/2506.05030/) (2025)
- [Overcoming Algorithm Aversion: A Comparison between Process and Outcome Control](https://mlsanity.com/paper/2303.12896/) (2023)
- [AI, Help Me Thinkunicodex2014but for Myself: Assisting People in Complex Decision-Making by Providing Different Kinds of Cognitive Support](https://mlsanity.com/paper/2504.06771/) (2025)
- [AI Mismatches: Identifying Potential Algorithmic Harms Before AI Development](https://mlsanity.com/paper/2502.18682/) (2025)
- [Does the "Artificial Intelligence Clinician" learn optimal treatment strategies for sepsis in intensive care?](https://mlsanity.com/paper/1902.03271/) (2019)
- [Sketching AI Concepts with Capabilities and Examples: AI Innovation in the Intensive Care Unit](https://mlsanity.com/paper/2402.13437/) (2024)
- [Tempo: Helping Data Scientists and Domain Experts Collaboratively Specify Predictive Modeling Tasks](https://mlsanity.com/paper/2502.10526/) (2025)
- [How Consistent are Clinicians? Evaluating the Predictability of Sepsis Disease Progression with Dynamics Models](https://mlsanity.com/paper/2404.07148/) (2024)

## Abstract (arXiv)

Artificial intelligence (AI)-based decision support systems can be highly accurate yet still fail to support users or improve decisions. Existing theories of AI-assisted decision-making focus on calibrating reliance on AI advice, leaving it unclear how different system designs might influence the reasoning processes underneath. We address this gap by reconsidering AI interfaces as collections of intelligent reasoning cues: discrete pieces of AI information that can individually influence decision-making. We then explore the roles of eight types of reasoning cues in a high-stakes clinical decision (treating patients with sepsis in intensive care). Through contextual inquiries with six teams and a think-aloud study with 25 physicians, we find that reasoning cues have distinct patterns of influence that can directly inform design. Our results also suggest that reasoning cues should prioritize tasks with high variability and discretion, adapt to ensure compatibility with evolving decision needs, and provide complementary, rigorous insights on complex cases.