# Self-Supervised Slice-to-Volume Reconstruction with Gaussian Representations for Fetal MRI

arXiv: https://arxiv.org/abs/2601.22990 · HTML: https://mlsanity.com/paper/2601.22990/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 7 of its 19 references that are in the map.
- First posted on arXiv 30 Jan 2026.

## Builds on (most cited first, 7 of 7)

- [3D Gaussian Splatting for Real-Time Radiance Field Rendering](https://mlsanity.com/paper/2308.04079/) (2023)
- [An automatic multi-tissue human fetal brain segmentation benchmark using the Fetal Tissue Annotation Dataset](https://mlsanity.com/paper/2010.15526/) (2020)
- [SVoRT: Iterative Transformer for Slice-to-Volume Registration in Fetal Brain MRI](https://mlsanity.com/paper/2206.10802/) (2022)
- [3DGR-CT: Sparse-View CT Reconstruction with a 3D Gaussian Representation](https://mlsanity.com/paper/2312.15676/) (2023)
- [3D Reconstruction in Canonical Co-ordinate Space from Arbitrarily Oriented 2D Images](https://mlsanity.com/paper/1709.06341/) (2017)
- [STRESS: Super-Resolution for Dynamic Fetal MRI using Self-Supervised Learning](https://mlsanity.com/paper/2106.12407/) (2021)
- [BridgeSplat: Bidirectionally Coupled CT and Non-Rigid Gaussian Splatting for Deformable Intraoperative Surgical Navigation](https://mlsanity.com/paper/2509.18501/) (2025)

## Abstract (arXiv)

Reconstructing 3D fetal MR volumes from motion-corrupted stacks of 2D slices is a crucial and challenging task. Conventional slice-to-volume reconstruction (SVR) methods are time-consuming and require multiple orthogonal stacks for reconstruction. While learning-based SVR approaches have significantly reduced the time required at the inference stage, they heavily rely on ground truth information for training, which is inaccessible in practice. To address these challenges, we propose GaussianSVR, a self-supervised framework for slice-to-volume reconstruction. GaussianSVR represents the target volume using 3D Gaussian representations to achieve high-fidelity reconstruction. It leverages a simulated forward slice acquisition model to enable self-supervised training, alleviating the need for ground-truth volumes. Furthermore, to enhance both accuracy and efficiency, we introduce a multi-resolution training strategy that jointly optimizes Gaussian parameters and spatial transformations across different resolution levels. Experiments show that GaussianSVR outperforms the baseline methods on fetal MR volumetric reconstruction. Code is available at https://github.com/Yinsong0510/GaussianSVR-Self-Supervised-Slice-to-Volume-Reconstruction-with-Gaussian-Representations.