# Neural-Inspired Posterior Approximation (NIPA)

arXiv: https://arxiv.org/abs/2601.22539 · HTML: https://mlsanity.com/paper/2601.22539/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 21 of its 91 references that are in the map.
- First posted on arXiv 30 Jan 2026.

## Builds on (most cited first, 21 of 21)

- [On Calibration of Modern Neural Networks](https://mlsanity.com/paper/1706.04599/) (2017)
- [Dropout as a Bayesian Approximation: Representing Model Uncertainty in Deep Learning](https://mlsanity.com/paper/1506.02142/) (2015)
- [Simple and Scalable Predictive Uncertainty Estimation using Deep Ensembles](https://mlsanity.com/paper/1612.01474/) (2016)
- [Variational Inference: A Review for Statisticians](https://mlsanity.com/paper/1601.00670/) (2016)
- [Averaging Weights Leads to Wider Optima and Better Generalization](https://mlsanity.com/paper/1803.05407/) (2018)
- [GPyTorch: Blackbox Matrix-Matrix Gaussian Process Inference with GPU Acceleration](https://mlsanity.com/paper/1809.11165/) (2018)
- [A Simple Baseline for Bayesian Uncertainty in Deep Learning](https://mlsanity.com/paper/1902.02476/) (2019)
- [Measuring Calibration in Deep Learning](https://mlsanity.com/paper/1904.01685/) (2019)
- [Stochastic Gradient Hamiltonian Monte Carlo](https://mlsanity.com/paper/1402.4102/) (2014)
- [Hands-on Bayesian Neural Networks -- a Tutorial for Deep Learning Users](https://mlsanity.com/paper/2007.06823/) (2020)
- [When Gaussian Process Meets Big Data: A Review of Scalable GPs](https://mlsanity.com/paper/1807.01065/) (2018)
- [Stochastic gradient Markov chain Monte Carlo](https://mlsanity.com/paper/1907.06986/) (2019)
- [GPS-ABC: Gaussian Process Surrogate Approximate Bayesian Computation](https://mlsanity.com/paper/1401.2838/) (2014)
- [Gradient-free Hamiltonian Monte Carlo with Efficient Kernel Exponential Families](https://mlsanity.com/paper/1506.02564/) (2015)
- [Variational Hamiltonian Monte Carlo via Score Matching](https://mlsanity.com/paper/1602.02219/) (2016)
- [Structured Stochastic Gradient MCMC](https://mlsanity.com/paper/2107.09028/) (2021)
- [Efficient and Generalizable Tuning Strategies for Stochastic Gradient MCMC](https://mlsanity.com/paper/2105.13059/) (2021)
- [Scaling Up Bayesian Uncertainty Quantification for Inverse Problems using Deep Neural Networks](https://mlsanity.com/paper/2101.03906/) (2021)
- [Variational MCMC](https://mlsanity.com/paper/1301.2266/) (2013)
- [Hamiltonian Monte Carlo Acceleration Using Surrogate Functions with Random Bases](https://mlsanity.com/paper/1506.05555/) (2015)
- [Coreset Markov Chain Monte Carlo](https://mlsanity.com/paper/2310.17063/) (2023)

## Abstract (arXiv)

Humans learn efficiently from their environment by engaging multiple interacting neural systems that support distinct yet complementary forms of control, including model-based (goal-directed) planning, model-free (habitual) responding, and episodic memory-based learning. Model-based mechanisms compute prospective action values using an internal model of the environment, supporting flexible but computationally costly planning; model-free mechanisms cache value estimates and build heuristics that enable fast, efficient habitual responding; and memory-based mechanisms allow rapid adaptation from individual experience. In this work, we aim to elucidate the computational principles underlying this biological efficiency and translate them into a sampling algorithm for scalable Bayesian inference through effective exploration of the posterior distribution. More specifically, our proposed algorithm comprises three components: a model-based module that uses the target distribution for guided but computationally slow sampling; a model-free module that uses previous samples to learn patterns in the parameter space, enabling fast, reflexive sampling without directly evaluating the expensive target distribution; and an episodic-control module that supports rapid sampling by recalling specific past events (i.e., samples). We show that this approach advances Bayesian methods and facilitates their application to large-scale statistical machine learning problems. In particular, we apply our proposed framework to Bayesian deep learning, with an emphasis on proper and principled uncertainty quantification.
