# CURE-Med: Curriculum-Informed Reinforcement Learning for Multilingual Medical Reasoning

arXiv: https://arxiv.org/abs/2601.13262 · HTML: https://mlsanity.com/paper/2601.13262/

## Key facts

- Cited by 9 papers in the map (data through 14 Oct 2026).
- Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning.
- Builds on 40 of its 72 references that are in the map.
- First posted on arXiv 19 Jan 2026.

## Placed in

- LLM reasoning / [Clinical and biomedical applications](https://mlsanity.com/lr/clinical-and-biomedical-applications/)

## Builds on (most cited first, 30 of 40)

- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [DeepSeekMath: Pushing the Limits of Mathematical Reasoning in Open Language Models](https://mlsanity.com/paper/2402.03300/) (2024)
- [DeepSeek-R1: Incentivizing Reasoning Capability in LLMs via Reinforcement Learning](https://mlsanity.com/paper/2501.12948/) (2025)
- [Qwen2.5 Technical Report](https://mlsanity.com/paper/2412.15115/) (2024)
- [Mistral 7B](https://mlsanity.com/paper/2310.06825/) (2023)
- [Gemma 2: Improving Open Language Models at a Practical Size](https://mlsanity.com/paper/2408.00118/) (2024)
- [OpenAI o1 System Card](https://mlsanity.com/paper/2412.16720/) (2024)
- [Super-NaturalInstructions: Generalization via Declarative Instructions on 1600+ NLP Tasks](https://mlsanity.com/paper/2204.07705/) (2022)
- [DeepSeek-V3 Technical Report](https://mlsanity.com/paper/2412.19437/) (2024)
- [Qwen2.5-Omni Technical Report](https://mlsanity.com/paper/2503.20215/) (2025)
- [Capabilities of GPT-4 on Medical Challenge Problems](https://mlsanity.com/paper/2303.13375/) (2023)
- [Instruction Tuning for Large Language Models: A Survey](https://mlsanity.com/paper/2308.10792/) (2023)
- [Towards Reasoning in Large Language Models: A Survey](https://mlsanity.com/paper/2212.10403/) (2022)
- [Language Models are Multilingual Chain-of-Thought Reasoners](https://mlsanity.com/paper/2210.03057/) (2022)
- [LIMO: Less is More for Reasoning](https://mlsanity.com/paper/2502.03387/) (2025)
- [Replacing Judges with Juries: Evaluating LLM Generations with a Panel of Diverse Models](https://mlsanity.com/paper/2404.18796/) (2024)
- [BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains](https://mlsanity.com/paper/2402.10373/) (2024)
- [MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Data](https://mlsanity.com/paper/2304.08247/) (2023)
- [MEDITRON-70B: Scaling Medical Pretraining for Large Language Models](https://mlsanity.com/paper/2311.16079/) (2023)
- [HuatuoGPT-o1, Towards Medical Complex Reasoning with LLMs](https://mlsanity.com/paper/2412.18925/) (2024)
- [ReFT: Reasoning with Reinforced Fine-Tuning](https://mlsanity.com/paper/2401.08967/) (2024)
- [HuatuoGPT, towards Taming Language Model to Be a Doctor](https://mlsanity.com/paper/2305.15075/) (2023)
- [TALM: Tool Augmented Language Models](https://mlsanity.com/paper/2205.12255/) (2022)
- [Crossing the Reward Bridge: Expanding RL with Verifiable Rewards Across Diverse Domains](https://mlsanity.com/paper/2503.23829/) (2025)
- [O1 Replication Journey -- Part 2: Surpassing O1-preview through Simple Distillation, Big Progress or Bitter Lesson?](https://mlsanity.com/paper/2411.16489/) (2024)
- [MAPO: Advancing Multilingual Reasoning through Multilingual Alignment-as-Preference Optimization](https://mlsanity.com/paper/2401.06838/) (2024)
- [LLMs Are Few-Shot In-Context Low-Resource Language Learners](https://mlsanity.com/paper/2403.16512/) (2024)
- [Breaking Language Barriers in Multilingual Mathematical Reasoning: Insights and Observations](https://mlsanity.com/paper/2310.20246/) (2023)
- [Democratizing LLMs for Low-Resource Languages by Leveraging their English Dominant Abilities with Linguistically-Diverse Prompts](https://mlsanity.com/paper/2306.11372/) (2023)

## Built on by (most cited first, 9 of 9)

- [CarePilot: A Multi-Agent Framework for Long-Horizon Computer Task Automation in Healthcare](https://mlsanity.com/paper/2603.24157/) (2026)
- [Efficient Multilingual Reasoning Transfer via Progressive Code-Switching](https://mlsanity.com/paper/2607.00485/) (2026)
- [When Background Matters: Breaking Medical Vision Language Models by Transferable Attack](https://mlsanity.com/paper/2604.17318/) (2026)
- [BhashaSutra: A Task-Centric Unified Survey of Indian NLP Datasets, Corpora, and Resources](https://mlsanity.com/paper/2604.18423/) (2026)
- [The Fragility of Chain-of-Thought Monitoring Across Typologically Diverse Languages](https://mlsanity.com/paper/2605.27901/) (2026)
- [HiMed: Incentivizing Hindi Reasoning in Medical LLMs](https://mlsanity.com/paper/2605.24635/) (2026)
- [PersuaRL: Reinforcement Learning-Driven Multi-Expert Selection for Persuasive Dialogue Generation in Insurance](https://mlsanity.com/paper/2609.01188/) (2026)
- [MMTClinic: Multimodal, Multilingual Time Series Question Answering and Reasoning Benchmark for Clinical Domain](https://mlsanity.com/paper/2609.04842/) (2026)
- [Building Multilingual Bridges: Data Mixing as the Pillar of Generalization for In-Language Reasoning](https://mlsanity.com/paper/2609.10445/) (2026)

## Abstract (arXiv)

While large language models (LLMs) have shown to perform well on monolingual mathematical and commonsense reasoning, they remain unreliable for multilingual medical reasoning applications, hindering their deployment in multilingual healthcare settings. We address this by first introducing CUREMED-BENCH, a high-quality multilingual medical reasoning dataset with open-ended reasoning queries with a single verifiable answer, spanning thirteen languages, including underrepresented languages such as Amharic, Yoruba, and Swahili. Building on this dataset, we propose CURE-MED, a curriculum-informed reinforcement learning framework that integrates code-switching-aware supervised fine-tuning and Group Relative Policy Optimization to jointly improve logical correctness and language stability. Across thirteen languages, our approach consistently outperforms strong baselines and scales effectively, achieving 85.21% language consistency and 54.35% logical correctness at 7B parameters, and 94.96% language consistency and 70.04% logical correctness at 32B parameters. These results support reliable and equitable multilingual medical reasoning in LLMs. The code and dataset are available at https://cure-med.github.io/