# Relation Extraction Capabilities of LLMs on Clinical Text: A Bilingual Evaluation for English and Turkish

arXiv: https://arxiv.org/abs/2601.09367 · HTML: https://mlsanity.com/paper/2601.09367/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 15 of its 42 references that are in the map.
- First posted on arXiv 14 Jan 2026.

## Builds on (most cited first, 15 of 15)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [RoBERTa: A Robustly Optimized BERT Pretraining Approach](https://mlsanity.com/paper/1907.11692/) (2019)
- [A Broad-Coverage Challenge Corpus for Sentence Understanding through Inference](https://mlsanity.com/paper/1704.05426/) (2017)
- [SimCSE: Simple Contrastive Learning of Sentence Embeddings](https://mlsanity.com/paper/2104.08821/) (2021)
- [BioBERT: a pre-trained biomedical language representation model for biomedical text mining](https://mlsanity.com/paper/1901.08746/) (2019)
- [MMLU-Pro: A More Robust and Challenging Multi-Task Language Understanding Benchmark](https://mlsanity.com/paper/2406.01574/) (2024)
- [A large annotated corpus for learning natural language inference](https://mlsanity.com/paper/1508.05326/) (2015)
- [What Makes Good In-Context Examples for GPT-3?](https://mlsanity.com/paper/2101.06804/) (2021)
- [Thinking about GPT-3 In-Context Learning for Biomedical IE? Think Again](https://mlsanity.com/paper/2203.08410/) (2022)
- [SemEval-2010 Task 8: Multi-Way Classification of Semantic Relations Between Pairs of Nominals](https://mlsanity.com/paper/1911.10422/) (2019)
- [Autoregressive Structured Prediction with Language Models](https://mlsanity.com/paper/2210.14698/) (2022)
- [Are Large Language Models Ready for Healthcare? A Comparative Study on Clinical Language Understanding](https://mlsanity.com/paper/2304.05368/) (2023)
- [Unleashing the Power of Large Language Models in Zero-shot Relation Extraction via Self-Prompting](https://mlsanity.com/paper/2410.01154/) (2024)
- [Are Small Language Models Ready to Compete with Large Language Models for Practical Applications?](https://mlsanity.com/paper/2406.11402/) (2024)

## Abstract (arXiv)

The scarcity of annotated datasets for clinical information extraction in non-English languages hinders the evaluation of large language model (LLM)-based methods developed primarily in English. In this study, we present the first comprehensive bilingual evaluation of LLMs for the clinical Relation Extraction (RE) task in both English and Turkish. To facilitate this evaluation, we introduce the first English-Turkish parallel clinical RE dataset, derived and carefully curated from the 2010 i2b2/VA relation classification corpus. We systematically assess a diverse set of prompting strategies, including multiple in-context learning (ICL) and Chain-of-Thought (CoT) approaches, and compare their performance to fine-tuned baselines such as PURE. Furthermore, we propose Relation-Aware Retrieval (RAR), a novel in-context example selection method based on contrastive learning, that is specifically designed to capture both sentence-level and relation-level semantics. Our results show that prompting-based LLM approaches consistently outperform traditional fine-tuned models. Moreover, evaluations for English performed better than their Turkish counterparts across all evaluated LLMs and prompting techniques. Among ICL methods, RAR achieves the highest performance, with Gemini 1.5 Flash reaching a micro-F1 score of 0.906 in English and 0.888 in Turkish. Performance further improves to 0.918 F1 in English when RAR is combined with a structured reasoning prompt using the DeepSeek-V3 model. These findings highlight the importance of high-quality demonstration retrieval and underscore the potential of advanced retrieval and prompting techniques to bridge resource gaps in clinical natural language processing.
