# UETQuintet at BioCreative IX -- MedHopQA: Enhancing Biomedical QA with Selective Multi-hop Reasoning and Contextual Retrieval

arXiv: https://arxiv.org/abs/2601.06974 · HTML: https://mlsanity.com/paper/2601.06974/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning.
- Builds on 10 of its 16 references that are in the map.
- First posted on arXiv 11 Jan 2026.

## Placed in

- LLM reasoning / [Clinical and biomedical applications](https://mlsanity.com/lr/clinical-and-biomedical-applications/)

## Builds on (most cited first, 10 of 10)

- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [SQuAD: 100,000+ Questions for Machine Comprehension of Text](https://mlsanity.com/paper/1606.05250/) (2016)
- [BioBERT: a pre-trained biomedical language representation model for biomedical text mining](https://mlsanity.com/paper/1901.08746/) (2019)
- [Large Language Models are Versatile Decomposers: Decompose Evidence and Questions for Table-based Reasoning](https://mlsanity.com/paper/2301.13808/) (2023)
- [Unsupervised Question Decomposition for Question Answering](https://mlsanity.com/paper/2002.09758/) (2020)
- [Biomedical Question Answering: A Survey of Approaches and Challenges](https://mlsanity.com/paper/2102.05281/) (2021)
- [Improving Medical Reasoning through Retrieval and Self-Reflection with Retrieval-Augmented Large Language Models](https://mlsanity.com/paper/2401.15269/) (2024)
- [MKRAG: Medical Knowledge Retrieval Augmented Generation for Medical Question Answering](https://mlsanity.com/paper/2309.16035/) (2023)
- [SearchRAG: Can Search Engines Be Helpful for LLM-based Medical Question Answering?](https://mlsanity.com/paper/2502.13233/) (2025)
- [Multi-hop Question Answering over Knowledge Graphs using Large Language Models](https://mlsanity.com/paper/2404.19234/) (2024)

## Abstract (arXiv)

Biomedical Question Answering systems play a critical role in processing complex medical queries, yet they often struggle with the intricate nature of medical data and the demand for multi-hop reasoning. In this paper, we propose a model designed to effectively address both direct and sequential questions. While sequential questions are decomposed into a chain of sub-questions to perform reasoning across a chain of steps, direct questions are processed directly to ensure efficiency and minimise processing overhead. Additionally, we leverage multi-source information retrieval and in-context learning to provide rich, relevant context for generating answers. We evaluated our model on the BioCreative IX - MedHopQA Shared Task datasets. Our approach achieves an Exact Match score of 0.84, ranking second on the current leaderboard. These results highlight the model's capability to meet the challenges of Biomedical Question Answering, offering a versatile solution for advancing medical research and practice.