# HemBLIP: A Vision-Language Model for Interpretable Leukemia Cell Morphology Analysis

arXiv: https://arxiv.org/abs/2601.03915 · HTML: https://mlsanity.com/paper/2601.03915/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models.
- Builds on 5 of its 26 references that are in the map.
- First posted on arXiv 7 Jan 2026.

## Placed in

- Multimodal LLMs / vision-language models / [Medical vision-language models](https://mlsanity.com/mllm/medical-vision-language-models/)

## Builds on (most cited first, 5 of 5)

- [BERTScore: Evaluating Text Generation with BERT](https://mlsanity.com/paper/1904.09675/) (2019)
- [BLIP: Bootstrapping Language-Image Pre-training for Unified Vision-Language Understanding and Generation](https://mlsanity.com/paper/2201.12086/) (2022)
- [MedGemma Technical Report](https://mlsanity.com/paper/2507.05201/) (2025)
- [Exploring the Frontier of Vision-Language Models: A Survey of Current Methodologies and Future Directions](https://mlsanity.com/paper/2404.07214/) (2024)
- [A Large-scale Multi Domain Leukemia Dataset for the White Blood Cells Detection with Morphological Attributes for Explainability](https://mlsanity.com/paper/2405.10803/) (2024)

## Built on by (most cited first, 1 of 1)

- [Multilingual Hematology Visual Question Answering Dataset](https://mlsanity.com/paper/2606.25246/) (2026)

## Abstract (arXiv)

Microscopic evaluation of white blood cell morphology is central to leukemia diagnosis, yet current deep learning models often act as black boxes, limiting clinical trust and adoption. We introduce HemBLIP, a vision language model designed to generate interpretable, morphology aware descriptions of peripheral blood cells. Using a newly constructed dataset of 14k healthy and leukemic cells paired with expert-derived attribute captions, we adapt a general-purpose VLM via both full fine-tuning and LoRA based parameter efficient training, and benchmark against the biomedical foundation model MedGEMMA. HemBLIP achieves higher caption quality and morphological accuracy, while LoRA adaptation provides further gains with significantly reduced computational cost. These results highlight the promise of vision language models for transparent and scalable hematological diagnostics.