# Towards Real-world Lens Active Alignment with Unlabeled Data via Domain Adaptation

arXiv: https://arxiv.org/abs/2601.03718 · HTML: https://mlsanity.com/paper/2601.03718/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 24 of its 35 references that are in the map.
- First posted on arXiv 7 Jan 2026.

## Builds on (most cited first, 24 of 24)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [A Simple Framework for Contrastive Learning of Visual Representations](https://mlsanity.com/paper/2002.05709/) (2020)
- [Taming Transformers for High-Resolution Image Synthesis](https://mlsanity.com/paper/2012.09841/) (2020)
- [Domain-Adversarial Training of Neural Networks](https://mlsanity.com/paper/1505.07818/) (2015)
- [Unsupervised Domain Adaptation by Backpropagation](https://mlsanity.com/paper/1409.7495/) (2014)
- [Learning Transferable Features with Deep Adaptation Networks](https://mlsanity.com/paper/1502.02791/) (2015)
- [Deep Visual Domain Adaptation: A Survey](https://mlsanity.com/paper/1802.03601/) (2018)
- [ADVENT: Adversarial Entropy Minimization for Domain Adaptation in Semantic Segmentation](https://mlsanity.com/paper/1811.12833/) (2018)
- [Deep Domain Confusion: Maximizing for Domain Invariance](https://mlsanity.com/paper/1412.3474/) (2014)
- [Learning to Adapt Structured Output Space for Semantic Segmentation](https://mlsanity.com/paper/1802.10349/) (2018)
- [Domain Adaptive Faster R-CNN for Object Detection in the Wild](https://mlsanity.com/paper/1803.03243/) (2018)
- [Contrastive Adaptation Network for Unsupervised Domain Adaptation](https://mlsanity.com/paper/1901.00976/) (2019)
- [Strong-Weak Distribution Alignment for Adaptive Object Detection](https://mlsanity.com/paper/1812.04798/) (2018)
- [Domain Randomization and Pyramid Consistency: Simulation-to-Real Generalization without Accessing Target Domain Data](https://mlsanity.com/paper/1909.00889/) (2019)
- [Deep Reconstruction-Classification Networks for Unsupervised Domain Adaptation](https://mlsanity.com/paper/1607.03516/) (2016)
- [Deep Subdomain Adaptation Network for Image Classification](https://mlsanity.com/paper/2106.09388/) (2021)
- [Blind Image Super-Resolution: A Survey and Beyond](https://mlsanity.com/paper/2107.03055/) (2021)
- [Unsupervised Domain Adaptation for Face Recognition in Unlabeled Videos](https://mlsanity.com/paper/1708.02191/) (2017)
- [Target-Independent Domain Adaptation for WBC Classification using Generative Latent Search](https://mlsanity.com/paper/2005.05432/) (2020)
- [Towards Unsupervised Domain Bridging via Image Degradation in Semantic Segmentation](https://mlsanity.com/paper/2412.10339/) (2024)
- [Representing Domain-Mixing Optical Degradation for Real-World Computational Aberration Correction via Vector Quantization](https://mlsanity.com/paper/2403.10012/) (2024)
- [Active Alignments of Lens Systems with Reinforcement Learning](https://mlsanity.com/paper/2503.02075/) (2025)
- [Deep Learning for Optical Misalignment Diagnostics in Multi-Lens Imaging Systems](https://mlsanity.com/paper/2506.23173/) (2025)

## Abstract (arXiv)

Active Alignment (AA) is a key technology for the large-scale automated assembly of high-precision optical systems. Compared with labor-intensive per-model on-device calibration, a digital-twin pipeline built on optical simulation offers a substantial advantage in generating large-scale labeled data. However, complex imaging conditions induce a domain gap between simulation and real-world images, limiting the generalization of simulation-trained models. To address this, we propose augmenting a simulation baseline with minimal unlabeled real-world images captured at random misalignment positions, mitigating the gap from a domain adaptation perspective. We introduce Domain Adaptive Active Alignment (DA3), which utilizes an autoregressive domain transformation generator and an adversarial-based feature alignment strategy to distill real-world domain information via self-supervised learning. This enables the extraction of domain-invariant image degradation features to facilitate robust misalignment prediction. Experiments on two lens types reveal that DA3 improves accuracy by 46% over a purely simulation pipeline. Notably, it approaches the performance achieved with precisely labeled real-world data collected on 3 lens samples, while reducing on-device data collection time by 98.7%. The results demonstrate that domain adaptation effectively endows simulation-trained models with robust real-world performance, validating the digital-twin pipeline as a practical solution to significantly enhance the efficiency of large-scale optical assembly.
