# Scale-aware Adaptive Supervised Network with Limited Medical Annotations

arXiv: https://arxiv.org/abs/2601.01005 · HTML: https://mlsanity.com/paper/2601.01005/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 25 of its 40 references that are in the map.
- First posted on arXiv 2 Jan 2026.

## Builds on (most cited first, 25 of 25)

- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [Temporal Ensembling for Semi-Supervised Learning](https://mlsanity.com/paper/1610.02242/) (2016)
- [ADVENT: Adversarial Entropy Minimization for Domain Adaptation in Semantic Segmentation](https://mlsanity.com/paper/1811.12833/) (2018)
- [Uncertainty-aware Self-ensembling Model for Semi-supervised 3D Left Atrium Segmentation](https://mlsanity.com/paper/1907.07034/) (2019)
- [Interpolation Consistency Training for Semi-Supervised Learning](https://mlsanity.com/paper/1903.03825/) (2019)
- [Semi-supervised Medical Image Segmentation through Dual-task Consistency](https://mlsanity.com/paper/2009.04448/) (2020)
- [Shape-aware Semi-supervised 3D Semantic Segmentation for Medical Images](https://mlsanity.com/paper/2007.10732/) (2020)
- [Bidirectional Copy-Paste for Semi-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2305.00673/) (2023)
- [LViT: Language meets Vision Transformer in Medical Image Segmentation](https://mlsanity.com/paper/2206.14718/) (2022)
- [Mutual Consistency Learning for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2109.09960/) (2021)
- [Efficient Semi-Supervised Gross Target Volume of Nasopharyngeal Carcinoma Segmentation via Uncertainty Rectified Pyramid Consistency](https://mlsanity.com/paper/2012.07042/) (2020)
- [SimCVD: Simple Contrastive Voxel-Wise Representation Distillation for Semi-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2108.06227/) (2021)
- [Local contrastive loss with pseudo-label based self-training for semi-supervised medical image segmentation](https://mlsanity.com/paper/2112.09645/) (2021)
- [Semi-Supervised Multi-Organ Segmentation via Deep Multi-Planar Co-Training](https://mlsanity.com/paper/1804.02586/) (2018)
- [DeepSeg: Deep Neural Network Framework for Automatic Brain Tumor Segmentation using Magnetic Resonance FLAIR Images](https://mlsanity.com/paper/2004.12333/) (2020)
- [VisionUnite: A Vision-Language Foundation Model for Ophthalmology Enhanced with Clinical Knowledge](https://mlsanity.com/paper/2408.02865/) (2024)
- [TFCNs: A CNN-Transformer Hybrid Network for Medical Image Segmentation](https://mlsanity.com/paper/2207.03450/) (2022)
- [Constructing and Exploring Intermediate Domains in Mixed Domain Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2404.08951/) (2024)
- [Anatomically-aware Uncertainty for Semi-supervised Image Segmentation](https://mlsanity.com/paper/2310.16099/) (2023)
- [Segment Together: A Versatile Paradigm for Semi-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2311.11686/) (2023)
- [Semi-supervised Semantic Segmentation with Multi-Constraint Consistency Learning](https://mlsanity.com/paper/2503.17914/) (2025)
- [Coarse-to-Fine Covid-19 Segmentation via Vision-Language Alignment](https://mlsanity.com/paper/2303.00279/) (2023)
- [Uncertainty-Participation Context Consistency Learning for Semi-supervised Semantic Segmentation](https://mlsanity.com/paper/2412.17331/) (2024)
- [STPNet: Scale-aware Text Prompt Network for Medical Image Segmentation](https://mlsanity.com/paper/2504.01561/) (2025)
- [An Intra- and Cross-frame Topological Consistency Scheme for Semi-supervised Atherosclerotic Coronary Plaque Segmentation](https://mlsanity.com/paper/2501.07850/) (2025)

## Built on by (most cited first, 1 of 1)

- [OPERA: Offline Policy-guided Expert Routing and Adaptation for Universal Biomedical Image Analysis](https://mlsanity.com/paper/2607.25108/) (2026)

## Abstract (arXiv)

Medical image segmentation faces critical challenges in semi-supervised learning scenarios due to severe annotation scarcity requiring expert radiological knowledge, significant inter-annotator variability across different viewpoints and expertise levels, and inadequate multi-scale feature integration for precise boundary delineation in complex anatomical structures. Existing semi-supervised methods demonstrate substantial performance degradation compared to fully supervised approaches, particularly in small target segmentation and boundary refinement tasks. To address these fundamental challenges, we propose SASNet (Scale-aware Adaptive Supervised Network), a dual-branch architecture that leverages both low-level and high-level feature representations through novel scale-aware adaptive reweight mechanisms. Our approach introduces three key methodological innovations, including the Scale-aware Adaptive Reweight strategy that dynamically weights pixel-wise predictions using temporal confidence accumulation, the View Variance Enhancement mechanism employing 3D Fourier domain transformations to simulate annotation variability, and segmentation-regression consistency learning through signed distance map algorithms for enhanced boundary precision. These innovations collectively address the core limitations of existing semi-supervised approaches by integrating spatial, temporal, and geometric consistency principles within a unified optimization framework. Comprehensive evaluation across LA, Pancreas-CT, and BraTS datasets demonstrates that SASNet achieves superior performance with limited labeled data, surpassing state-of-the-art semi-supervised methods while approaching fully supervised performance levels. The source code for SASNet is available at https://github.com/HUANGLIZI/SASNet.