# An Adaptive, Disentangled Representation for Multidimensional MRI Reconstruction

arXiv: https://arxiv.org/abs/2512.24674 · HTML: https://mlsanity.com/paper/2512.24674/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 29 of its 53 references that are in the map.
- First posted on arXiv 31 Dec 2025.

## Builds on (most cited first, 29 of 29)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Denoising Diffusion Implicit Models](https://mlsanity.com/paper/2010.02502/) (2020)
- [A Style-Based Generator Architecture for Generative Adversarial Networks](https://mlsanity.com/paper/1812.04948/) (2018)
- [Flow Matching for Generative Modeling](https://mlsanity.com/paper/2210.02747/) (2022)
- [Generative Modeling by Estimating Gradients of the Data Distribution](https://mlsanity.com/paper/1907.05600/) (2019)
- [Analyzing and Improving the Image Quality of StyleGAN](https://mlsanity.com/paper/1912.04958/) (2019)
- [FiLM: Visual Reasoning with a General Conditioning Layer](https://mlsanity.com/paper/1709.07871/) (2017)
- [Diffusion Posterior Sampling for General Noisy Inverse Problems](https://mlsanity.com/paper/2209.14687/) (2022)
- [Deep Image Prior](https://mlsanity.com/paper/1711.10925/) (2017)
- [Algorithm Unrolling: Interpretable, Efficient Deep Learning for Signal and Image Processing](https://mlsanity.com/paper/1912.10557/) (2019)
- [MoDL: Model Based Deep Learning Architecture for Inverse Problems](https://mlsanity.com/paper/1712.02862/) (2017)
- [Learning a Variational Network for Reconstruction of Accelerated MRI Data](https://mlsanity.com/paper/1704.00447/) (2017)
- [Compressed Sensing using Generative Models](https://mlsanity.com/paper/1703.03208/) (2017)
- [Solving Inverse Problems with Latent Diffusion Models via Hard Data Consistency](https://mlsanity.com/paper/2307.08123/) (2023)
- [Adaptive Diffusion Priors for Accelerated MRI Reconstruction](https://mlsanity.com/paper/2207.05876/) (2022)
- [Plug-and-Play Methods for Integrating Physical and Learned Models in Computational Imaging](https://mlsanity.com/paper/2203.17061/) (2022)
- [Time-Dependent Deep Image Prior for Dynamic MRI](https://mlsanity.com/paper/1910.01684/) (2019)
- [Disentangled Representation Learning in Cardiac Image Analysis](https://mlsanity.com/paper/1903.09467/) (2019)
- [Zero-Shot Self-Supervised Learning for MRI Reconstruction](https://mlsanity.com/paper/2102.07737/) (2021)
- [Measuring Robustness in Deep Learning Based Compressive Sensing](https://mlsanity.com/paper/2102.06103/) (2021)
- [Image-Adaptive GAN based Reconstruction](https://mlsanity.com/paper/1906.05284/) (2019)
- [A theoretical framework for self-supervised MR image reconstruction using sub-sampling via variable density Noisier2Noise](https://mlsanity.com/paper/2205.10278/) (2022)
- [Representation Disentanglement for Multi-modal brain MR Analysis](https://mlsanity.com/paper/2102.11456/) (2021)
- [Prior Image-Constrained Reconstruction using Style-Based Generative Models](https://mlsanity.com/paper/2102.12525/) (2021)
- [Unsupervised Deep Learning Methods for Biological Image Reconstruction and Enhancement](https://mlsanity.com/paper/2105.08040/) (2021)
- [Unified cross-modality feature disentangler for unsupervised multi-domain MRI abdomen organs segmentation](https://mlsanity.com/paper/2007.09669/) (2020)
- [Zero-Shot Self-Supervised Joint Temporal Image and Sensitivity Map Reconstruction via Linear Latent Space](https://mlsanity.com/paper/2303.02254/) (2023)

## Built on by (most cited first, 1 of 1)

- [Learning Subject-Specific Anatomical Representations via Manifold Expansion: Application to Accelerated Multi-Contrast MRI](https://mlsanity.com/paper/2610.04028/) (2026)

## Abstract (arXiv)

We present a new approach for representing and reconstructing multidimensional magnetic resonance imaging (MRI) data. Our method builds on a novel, learned feature-based image representation that disentangles different types of features, such as geometry and contrast, into distinct low-dimensional latent spaces, enabling better exploitation of feature correlations in multidimensional images and incorporation of pre-learned priors specific to different feature types for reconstruction. More specifically, the disentanglement was achieved via an encoderdecoder network and image transfer training using large public data, enhanced by a style-based decoder design. A latent diffusion model was introduced to impose stronger constraints on distinct feature spaces. New reconstruction formulations and algorithms were developed to integrate the learned representation with a zero-shot selfsupervised learning adaptation and subspace modeling. The proposed method has been evaluated on accelerated T1 and T2 parameter mapping, achieving improved performance over state-of-the-art reconstruction methods, without task-specific supervised training or fine-tuning. This work offers a new strategy for learning-based multidimensional image reconstruction where only limited data are available for problem-specific or task-specific training.