# INFORM-CT: INtegrating LLMs and VLMs FOR Incidental Findings Management in Abdominal CT

arXiv: https://arxiv.org/abs/2512.14732 · HTML: https://mlsanity.com/paper/2512.14732/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 14 of its 23 references that are in the map.
- First posted on arXiv 10 Dec 2025.

## Builds on (most cited first, 14 of 14)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [ReAct: Synergizing Reasoning and Acting in Language Models](https://mlsanity.com/paper/2210.03629/) (2022)
- [TotalSegmentator: robust segmentation of 104 anatomical structures in CT images](https://mlsanity.com/paper/2208.05868/) (2022)
- [ViperGPT: Visual Inference via Python Execution for Reasoning](https://mlsanity.com/paper/2303.08128/) (2023)
- [Visual Programming: Compositional visual reasoning without training](https://mlsanity.com/paper/2211.11559/) (2022)
- [GANomaly: Semi-Supervised Anomaly Detection via Adversarial Training](https://mlsanity.com/paper/1805.06725/) (2018)
- [Generalist Foundation Models from a Multimodal Dataset for 3D Computed Tomography](https://mlsanity.com/paper/2403.17834/) (2024)
- [Merlin: A Computed Tomography Vision-Language Foundation Model and Dataset](https://mlsanity.com/paper/2406.06512/) (2024)
- [MoReVQA: Exploring Modular Reasoning Models for Video Question Answering](https://mlsanity.com/paper/2404.06511/) (2024)
- [Anomaly Detection in Medical Imaging with Deep Perceptual Autoencoders](https://mlsanity.com/paper/2006.13265/) (2020)
- [BIMCV-R: A Landmark Dataset for 3D CT Text-Image Retrieval](https://mlsanity.com/paper/2403.15992/) (2024)
- [HYDRA: A Hyper Agent for Dynamic Compositional Visual Reasoning](https://mlsanity.com/paper/2403.12884/) (2024)
- [Self-Training Large Language Models for Improved Visual Program Synthesis With Visual Reinforcement](https://mlsanity.com/paper/2404.04627/) (2024)
- [cOOpD: Reformulating COPD classification on chest CT scans as anomaly detection using contrastive representations](https://mlsanity.com/paper/2307.07254/) (2023)

## Built on by (most cited first, 1 of 1)

- [Volumetric Radiology AI in the Era of Multimodal Large Language Models](https://mlsanity.com/paper/2608.20549/) (2026)

## Abstract (arXiv)

Incidental findings in CT scans, though often benign, can have significant clinical implications and should be reported following established guidelines. Traditional manual inspection by radiologists is time-consuming and variable. This paper proposes a novel framework that leverages large language models (LLMs) and foundational vision-language models (VLMs) in a plan-and-execute agentic approach to improve the efficiency and precision of incidental findings detection, classification, and reporting for abdominal CT scans. Given medical guidelines for abdominal organs, the process of managing incidental findings is automated through a planner-executor framework. The planner, based on LLM, generates Python scripts using predefined base functions, while the executor runs these scripts to perform the necessary checks and detections, via VLMs, segmentation models, and image processing subroutines. We demonstrate the effectiveness of our approach through experiments on a CT abdominal benchmark for three organs, in a fully automatic end-to-end manner. Our results show that the proposed framework outperforms existing pure VLM-based approaches in terms of accuracy and efficiency.