# Leveraging LLMs for Structured Data Extraction from Unstructured Patient Records

arXiv: https://arxiv.org/abs/2512.13700 · HTML: https://mlsanity.com/paper/2512.13700/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 8 of its 18 references that are in the map.
- First posted on arXiv 3 Dec 2025.

## Builds on (most cited first, 8 of 8)

- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Qwen3 Technical Report](https://mlsanity.com/paper/2505.09388/) (2025)
- [Efficient Memory Management for Large Language Model Serving with PagedAttention](https://mlsanity.com/paper/2309.06180/) (2023)
- [Lost in the Middle: How Language Models Use Long Contexts](https://mlsanity.com/paper/2307.03172/) (2023)
- [Billion-scale similarity search with GPUs](https://mlsanity.com/paper/1702.08734/) (2017)
- [MPNet: Masked and Permuted Pre-training for Language Understanding](https://mlsanity.com/paper/2004.09297/) (2020)
- [CHiLL: Zero-shot Custom Interpretable Feature Extraction from Clinical Notes with Large Language Models](https://mlsanity.com/paper/2302.12343/) (2023)

## Built on by (most cited first, 1 of 1)

- [Neurosymbolic Clinical Trial Matching via LLM-Driven Abduction and Logical Verification](https://mlsanity.com/paper/2606.20895/) (2026)

## Abstract (arXiv)

Manual chart review remains an extremely time-consuming and resource-intensive component of clinical research, requiring experts to extract often complex information from unstructured electronic health record (EHR) narratives. We present a secure, modular framework for automated structured feature extraction from clinical notes leveraging locally deployed large language models (LLMs) on institutionally approved, Health Insurance Portability and Accountability Act (HIPPA)-compliant compute infrastructure. This system integrates retrieval augmented generation (RAG) and structured response methods of LLMs into a widely deployable and scalable container to provide feature extraction for diverse clinical domains. In evaluation, the framework achieved high accuracy across multiple medical characteristics present in large bodies of patient notes when compared against an expert-annotated dataset and identified several annotation errors missed in manual review. This framework demonstrates the potential of LLM systems to reduce the burden of manual chart review through automated extraction and increase consistency in data capture, accelerating clinical research.