# LDP: Parameter-Efficient Fine-Tuning of Multimodal LLM for Medical Report Generation

arXiv: https://arxiv.org/abs/2512.10750 · HTML: https://mlsanity.com/paper/2512.10750/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 9 of its 19 references that are in the map.
- First posted on arXiv 11 Dec 2025.

## Builds on (most cited first, 9 of 9)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Direct Preference Optimization: Your Language Model is Secretly a Reward Model](https://mlsanity.com/paper/2305.18290/) (2023)
- [Show, Attend and Tell: Neural Image Caption Generation with Visual Attention](https://mlsanity.com/paper/1502.03044/) (2015)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [Hybrid Retrieval-Generation Reinforced Agent for Medical Image Report Generation](https://mlsanity.com/paper/1805.08298/) (2018)
- [TieNet: Text-Image Embedding Network for Common Thorax Disease Classification and Reporting in Chest X-rays](https://mlsanity.com/paper/1801.04334/) (2018)
- [Dia-LLaMA: Towards Large Language Model-driven CT Report Generation](https://mlsanity.com/paper/2403.16386/) (2024)
- [Variational Topic Inference for Chest X-Ray Report Generation](https://mlsanity.com/paper/2107.07314/) (2021)

## Built on by (most cited first, 1 of 1)

- [Fine-tuning a multimodal large language model for clinician-grade autism behavioral scoring from short home videos](https://mlsanity.com/paper/2606.27484/) (2026)

## Abstract (arXiv)

Colonoscopic polyp diagnosis is pivotal for early colorectal cancer detection, yet traditional automated reporting suffers from inconsistencies and hallucinations due to the scarcity of high-quality multimodal medical data. To bridge this gap, we propose LDP, a novel framework leveraging multimodal large language models (MLLMs) for professional polyp diagnosis report generation. Specifically, we curate MMEndo, a multimodal endoscopic dataset comprising expert-annotated colonoscopy image-text pairs. We fine-tune the Qwen2-VL-7B backbone using Parameter-Efficient Fine-Tuning (LoRA) and align it with clinical standards via Direct Preference Optimization (DPO). Extensive experiments show that our LDP outperforms existing baselines on both automated metrics and rigorous clinical expert evaluations (achieving a Physician Score of 7.2/10), significantly reducing training computational costs by 833x compared to full fine-tuning. The proposed solution offers a scalable, clinically viable path for primary healthcare, with additional validation on the IU-XRay dataset confirming its robustness.