# Inverse problems with diffusion models: MAP estimation via mode-seeking loss

arXiv: https://arxiv.org/abs/2512.10524 · HTML: https://mlsanity.com/paper/2512.10524/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Placed in Inverse problems and image restoration, one of 14 directions in Diffusion models.
- Builds on 26 of its 33 references that are in the map.
- First posted on arXiv 11 Dec 2025.

## Placed in

- Diffusion models / [Inverse problems and image restoration](https://mlsanity.com/diffusion/inverse-problems-and-image-restoration/)

## Builds on (most cited first, 26 of 26)

- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [The Unreasonable Effectiveness of Deep Features as a Perceptual Metric](https://mlsanity.com/paper/1801.03924/) (2018)
- [Denoising Diffusion Implicit Models](https://mlsanity.com/paper/2010.02502/) (2020)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [ImageNet Large Scale Visual Recognition Challenge](https://mlsanity.com/paper/1409.0575/) (2014)
- [A Style-Based Generator Architecture for Generative Adversarial Networks](https://mlsanity.com/paper/1812.04948/) (2018)
- [Deep Learning Face Attributes in the Wild](https://mlsanity.com/paper/1411.7766/) (2014)
- [Elucidating the Design Space of Diffusion-Based Generative Models](https://mlsanity.com/paper/2206.00364/) (2022)
- [Consistency Models](https://mlsanity.com/paper/2303.01469/) (2023)
- [Diffusion Posterior Sampling for General Noisy Inverse Problems](https://mlsanity.com/paper/2209.14687/) (2022)
- [Denoising Diffusion Restoration Models](https://mlsanity.com/paper/2201.11793/) (2022)
- [Sliced Score Matching: A Scalable Approach to Density and Score Estimation](https://mlsanity.com/paper/1905.07088/) (2019)
- [Denoising Diffusion Models for Plug-and-Play Image Restoration](https://mlsanity.com/paper/2305.08995/) (2023)
- [Diffusion probabilistic modeling of protein backbones in 3D for the motif-scaffolding problem](https://mlsanity.com/paper/2206.04119/) (2022)
- [A Variational Perspective on Solving Inverse Problems with Diffusion Models](https://mlsanity.com/paper/2305.04391/) (2023)
- [Solving Inverse Problems with Latent Diffusion Models via Hard Data Consistency](https://mlsanity.com/paper/2307.08123/) (2023)
- [Improving Diffusion Inverse Problem Solving with Decoupled Noise Annealing](https://mlsanity.com/paper/2407.01521/) (2024)
- [Solving Linear Inverse Problems Provably via Posterior Sampling with Latent Diffusion Models](https://mlsanity.com/paper/2307.00619/) (2023)
- [Monte Carlo guided Diffusion for Bayesian linear inverse problems](https://mlsanity.com/paper/2308.07983/) (2023)
- [DMPlug: A Plug-in Method for Solving Inverse Problems with Diffusion Models](https://mlsanity.com/paper/2405.16749/) (2024)
- [Improving Diffusion Models for Inverse Problems Using Optimal Posterior Covariance](https://mlsanity.com/paper/2402.02149/) (2024)
- [Variational Diffusion Posterior Sampling with Midpoint Guidance](https://mlsanity.com/paper/2410.09945/) (2024)
- [Repulsive Latent Score Distillation for Solving Inverse Problems](https://mlsanity.com/paper/2406.16683/) (2024)
- [Inverse Problems with Diffusion Models: A MAP Estimation Perspective](https://mlsanity.com/paper/2407.20784/) (2024)
- [Inverse Problem Sampling in Latent Space Using Sequential Monte Carlo](https://mlsanity.com/paper/2502.05908/) (2025)

## Built on by (most cited first, 1 of 1)

- [Beyond MMSE: Enhancing PnP Restoration with ProxiMAP](https://mlsanity.com/paper/2605.16396/) (2026)

## Abstract (arXiv)

A pre-trained unconditional diffusion model, combined with posterior sampling or maximum a posteriori (MAP) estimation techniques, can solve arbitrary inverse problems without task-specific training or fine-tuning. However, existing posterior sampling and MAP estimation methods often rely on modeling approximations and can also be computationally demanding. In this work, we propose a new MAP estimation strategy for solving inverse problems with a pre-trained unconditional diffusion model. Specifically, we introduce the variational mode-seeking loss (VML) and show that its minimization at each reverse diffusion step guides the generated sample towards the MAP estimate (modes in practice). VML arises from a novel perspective of minimizing the Kullback-Leibler (KL) divergence between the diffusion posterior p(x0|xt) and the measurement posterior p(x0|y), where y denotes the measurement. Importantly, for linear inverse problems, VML can be analytically derived without any modeling approximations. Based on further theoretical insights, we propose VML-MAP, an empirically effective algorithm for solving inverse problems via VML minimization, and validate its efficacy in both performance and computational time through extensive experiments on diverse image-restoration tasks across multiple datasets.