# Effective Attention-Guided Multi-Scale Medical Network for Skin Lesion Segmentation

arXiv: https://arxiv.org/abs/2512.07275 · HTML: https://mlsanity.com/paper/2512.07275/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 16 of its 26 references that are in the map.
- First posted on arXiv 8 Dec 2025.

## Builds on (most cited first, 16 of 16)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentation](https://mlsanity.com/paper/2105.05537/) (2021)
- [Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1902.03368/) (2019)
- [GhostNet: More Features from Cheap Operations](https://mlsanity.com/paper/1911.11907/) (2019)
- [Beyond Self-attention: External Attention using Two Linear Layers for Visual Tasks](https://mlsanity.com/paper/2105.02358/) (2021)
- [NDC-Scene: Boost Monocular 3D Semantic Scene Completion in Normalized Device Coordinates Space](https://mlsanity.com/paper/2309.14616/) (2023)
- [CA-Net: Comprehensive Attention Convolutional Neural Networks for Explainable Medical Image Segmentation](https://mlsanity.com/paper/2009.10549/) (2020)
- [Optimizing the Dice Score and Jaccard Index for Medical Image Segmentation: Theory & Practice](https://mlsanity.com/paper/1911.01685/) (2019)
- [Swift Sampler: Efficient Learning of Sampler by 10 Parameters](https://mlsanity.com/paper/2410.05578/) (2024)
- [Geodesic Prototype Matching via Diffusion Maps for Interpretable Fine-Grained Recognition](https://mlsanity.com/paper/2509.17050/) (2025)
- [C3-OWD: A Curriculum Cross-modal Contrastive Learning Framework for Open-World Detection](https://mlsanity.com/paper/2509.23316/) (2025)
- [RTGMFF: Enhanced fMRI-based Brain Disorder Diagnosis via ROI-driven Text Generation and Multimodal Feature Fusion](https://mlsanity.com/paper/2509.03214/) (2025)

## Abstract (arXiv)

In the field of healthcare, precise skin lesion segmentation is crucial for the early detection and accurate diagnosis of skin diseases. Despite significant advances in deep learning for image processing, existing methods have yet to effectively address the challenges of irregular lesion shapes and low contrast. To address these issues, this paper proposes an innovative encoder-decoder network architecture based on multi-scale residual structures, capable of extracting rich feature information from different receptive fields to effectively identify lesion areas. By introducing a Multi-Resolution Multi-Channel Fusion (MRCF) module, our method captures cross-scale features, enhancing the clarity and accuracy of the extracted information. Furthermore, we propose a Cross-Mix Attention Module (CMAM), which redefines the attention scope and dynamically calculates weights across multiple contexts, thus improving the flexibility and depth of feature capture and enabling deeper exploration of subtle features. To overcome the information loss caused by skip connections in traditional U-Net, an External Attention Bridge (EAB) is introduced, facilitating the effective utilization of information in the decoder and compensating for the loss during upsampling. Extensive experimental evaluations on several skin lesion segmentation datasets demonstrate that the proposed model significantly outperforms existing transformer and convolutional neural network-based models, showcasing exceptional segmentation accuracy and robustness.