# Equivariant symmetry-aware head pose estimation for fetal MRI

arXiv: https://arxiv.org/abs/2512.04890 · HTML: https://mlsanity.com/paper/2512.04890/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 45 of its 92 references that are in the map.
- First posted on arXiv 4 Dec 2025.

## Builds on (most cited first, 30 of 45)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [On the Continuity of Rotation Representations in Neural Networks](https://mlsanity.com/paper/1812.07035/) (2018)
- [Group Equivariant Convolutional Networks](https://mlsanity.com/paper/1602.07576/) (2016)
- [Fast and Accurate Deep Network Learning by Exponential Linear Units (ELUs)](https://mlsanity.com/paper/1511.07289/) (2015)
- [PoseCNN: A Convolutional Neural Network for 6D Object Pose Estimation in Cluttered Scenes](https://mlsanity.com/paper/1711.00199/) (2017)
- [Tensor field networks: Rotation- and translation-equivariant neural networks for 3D point clouds](https://mlsanity.com/paper/1802.08219/) (2018)
- [Spherical CNNs](https://mlsanity.com/paper/1801.10130/) (2018)
- [General E(2)-Equivariant Steerable CNNs](https://mlsanity.com/paper/1911.08251/) (2019)
- [3D Steerable CNNs: Learning Rotationally Equivariant Features in Volumetric Data](https://mlsanity.com/paper/1807.02547/) (2018)
- [Steerable CNNs](https://mlsanity.com/paper/1612.08498/) (2016)
- [Vector Neurons: A General Framework for SO(3)-Equivariant Networks](https://mlsanity.com/paper/2104.12229/) (2021)
- [Harmonic Networks: Deep Translation and Rotation Equivariance](https://mlsanity.com/paper/1612.04642/) (2016)
- [SynthSeg: Segmentation of brain MRI scans of any contrast and resolution without retraining](https://mlsanity.com/paper/2107.09559/) (2021)
- [TorchIO: A Python library for efficient loading, preprocessing, augmentation and patch-based sampling of medical images in deep learning](https://mlsanity.com/paper/2003.04696/) (2020)
- [e3nn: Euclidean Neural Networks](https://mlsanity.com/paper/2207.09453/) (2022)
- [EPOS: Estimating 6D Pose of Objects with Symmetries](https://mlsanity.com/paper/2004.00605/) (2020)
- [Approximately Equivariant Networks for Imperfectly Symmetric Dynamics](https://mlsanity.com/paper/2201.11969/) (2022)
- [An Analysis of SVD for Deep Rotation Estimation](https://mlsanity.com/paper/2006.14616/) (2020)
- [Equivariant Point Network for 3D Point Cloud Analysis](https://mlsanity.com/paper/2103.14147/) (2021)
- [Probabilistic 3D Multi-Modal, Multi-Object Tracking for Autonomous Driving](https://mlsanity.com/paper/2012.13755/) (2020)
- [Leveraging SE(3) Equivariance for Self-Supervised Category-Level Object Pose Estimation](https://mlsanity.com/paper/2111.00190/) (2021)
- [Learning with 3D rotations, a hitchhiker's guide to SO(3)](https://mlsanity.com/paper/2404.11735/) (2024)
- [Real-time Deep Pose Estimation with Geodesic Loss for Image-to-Template Rigid Registration](https://mlsanity.com/paper/1803.05982/) (2018)
- [Improved Generalization Bounds of Group Invariant / Equivariant Deep Networks via Quotient Feature Spaces](https://mlsanity.com/paper/1910.06552/) (2019)
- [On Object Symmetries and 6D Pose Estimation from Images](https://mlsanity.com/paper/1908.07640/) (2019)
- [6D Object Pose Regression via Supervised Learning on Point Clouds](https://mlsanity.com/paper/2001.08942/) (2020)
- [Self-Supervised Equivariant Learning for Oriented Keypoint Detection](https://mlsanity.com/paper/2204.08613/) (2022)
- [SVoRT: Iterative Transformer for Slice-to-Volume Registration in Fetal Brain MRI](https://mlsanity.com/paper/2206.10802/) (2022)
- [A Robust and Interpretable Deep Learning Framework for Multi-modal Registration via Keypoints](https://mlsanity.com/paper/2304.09941/) (2023)

## Abstract (arXiv)

We present E(3)-Pose, a novel fast pose estimation method that jointly and explicitly models rotation equivariance and object symmetry. Our work is motivated by the challenging problem of accounting for fetal head motion during a diagnostic MRI scan. We aim to enable automatic adaptive prescription of diagnostic 2D MRI slices with 6-DoF head pose estimation, supported by rapid low-resolution 3D MRI volumes acquired before each 2D slice. Existing pose estimation methods struggle to generalize to clinical volumes due to pose ambiguities induced by inherent anatomical symmetries, as well as low resolution, noise, and artifacts. In contrast, E(3)-Pose captures anatomical symmetries and rigid pose equivariance by construction, and yields robust estimates of the fetal head pose. Our experiments on publicly available and representative clinical fetal MRI datasets demonstrate the superior robustness and generalization of our method across domains. Crucially, E(3)-Pose achieves state-of-the-art accuracy on clinical MRI volumes, supporting future clinical translation. Our implementation is publicly available at github.com/MedicalVisionGroup/E3-Pose.
