# Language Models as Semantic Teachers: Post-Training Alignment for Medical Audio Understanding

arXiv: https://arxiv.org/abs/2512.04847 · HTML: https://mlsanity.com/paper/2512.04847/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 29 of its 39 references that are in the map.
- First posted on arXiv 4 Dec 2025.

## Builds on (most cited first, 29 of 29)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [Distilling the Knowledge in a Neural Network](https://mlsanity.com/paper/1503.02531/) (2015)
- [DeepSeek-R1: Incentivizing Reasoning Capability in LLMs via Reinforcement Learning](https://mlsanity.com/paper/2501.12948/) (2025)
- [Qwen Technical Report](https://mlsanity.com/paper/2309.16609/) (2023)
- [Similarity of Neural Network Representations Revisited](https://mlsanity.com/paper/1905.00414/) (2019)
- [ImageBind: One Embedding Space To Bind Them All](https://mlsanity.com/paper/2305.05665/) (2023)
- [Qwen2.5-Omni Technical Report](https://mlsanity.com/paper/2503.20215/) (2025)
- [AudioLM: a Language Modeling Approach to Audio Generation](https://mlsanity.com/paper/2209.03143/) (2022)
- [Mind the Gap: Understanding the Modality Gap in Multi-modal Contrastive Representation Learning](https://mlsanity.com/paper/2203.02053/) (2022)
- [Understanding Dimensional Collapse in Contrastive Self-supervised Learning](https://mlsanity.com/paper/2110.09348/) (2021)
- [The Faiss library](https://mlsanity.com/paper/2401.08281/) (2024)
- [AudioCLIP: Extending CLIP to Image, Text and Audio](https://mlsanity.com/paper/2106.13043/) (2021)
- [SmolLM2: When Smol Goes Big -- Data-Centric Training of a Small Language Model](https://mlsanity.com/paper/2502.02737/) (2025)
- [AudioGen: Textually Guided Audio Generation](https://mlsanity.com/paper/2209.15352/) (2022)
- [Masked Autoencoders that Listen](https://mlsanity.com/paper/2207.06405/) (2022)
- [Contrastive Learning of General-Purpose Audio Representations](https://mlsanity.com/paper/2010.10915/) (2020)
- [jina-embeddings-v4: Universal Embeddings for Multimodal Multilingual Retrieval](https://mlsanity.com/paper/2506.18902/) (2025)
- [UniCLIP: Unified Framework for Contrastive Language-Image Pre-training](https://mlsanity.com/paper/2209.13430/) (2022)
- [COLA: A Benchmark for Compositional Text-to-image Retrieval](https://mlsanity.com/paper/2305.03689/) (2023)
- [Revisiting Multimodal Representation in Contrastive Learning: From Patch and Token Embeddings to Finite Discrete Tokens](https://mlsanity.com/paper/2303.14865/) (2023)
- [AugLy: Data Augmentations for Robustness](https://mlsanity.com/paper/2201.06494/) (2022)
- [The CirCor DigiScope Dataset: From Murmur Detection to Murmur Classification](https://mlsanity.com/paper/2108.00813/) (2021)
- [Towards Open Respiratory Acoustic Foundation Models: Pretraining and Benchmarking](https://mlsanity.com/paper/2406.16148/) (2024)
- [Post-pre-training for Modality Alignment in Vision-Language Foundation Models](https://mlsanity.com/paper/2504.12717/) (2025)
- [SSR: Alignment-Aware Modality Connector for Speech Language Models](https://mlsanity.com/paper/2410.00168/) (2024)
- [Speech-Text Dialog Pre-training for Spoken Dialog Understanding with Explicit Cross-Modal Alignment](https://mlsanity.com/paper/2305.11579/) (2023)
- [RespLLM: Unifying Audio and Text with Multimodal LLMs for Generalized Respiratory Health Prediction](https://mlsanity.com/paper/2410.05361/) (2024)

## Built on by (most cited first, 1 of 1)

- [Adaptive Test-Time Scaling for Zero-Shot Respiratory Audio Classification](https://mlsanity.com/paper/2604.12647/) (2026)

## Abstract (arXiv)

Pre-trained audio models excel at detecting acoustic patterns in auscultation sounds but often fail to grasp their clinical significance, limiting their use and performance in diagnostic tasks. To bridge this gap, we introduce AcuLa (Audio-Clinical Understanding via Language Alignment), a lightweight post-training framework that instills semantic understanding into any audio encoder by aligning it with a medical language model, which acts as a "semantic teacher." To enable alignment at scale, we construct a large-scale dataset by leveraging off-the-shelf large language models to translate the rich, structured metadata accompanying existing audio recordings into coherent clinical reports. Our alignment strategy combines a representation-level contrastive objective with a self-supervised modeling, ensuring that the model learns clinical semantics while preserving fine-grained temporal cues. AcuLa achieves state-of-the-art results across 18 diverse cardio-respiratory tasks from 10 different datasets, improving the mean AUROC on classification benchmarks from 0.68 to 0.79 and, on the most challenging COVID-19 cough detection task, boosting the AUROC from 0.55 to 0.89. Our work demonstrates that this audio-language alignment transforms purely acoustic models into clinically-aware diagnostic tools, establishing a novel paradigm for enhancing physiological understanding in audio-based health monitoring.
