# Data-Centric Visual Development for Self-Driving Labs

arXiv: https://arxiv.org/abs/2512.02018 · HTML: https://mlsanity.com/paper/2512.02018/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 21 of its 40 references that are in the map.
- First posted on arXiv 1 Dec 2025.

## Builds on (most cited first, 21 of 21)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [ImageNet Large Scale Visual Recognition Challenge](https://mlsanity.com/paper/1409.0575/) (2014)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [A Style-Based Generator Architecture for Generative Adversarial Networks](https://mlsanity.com/paper/1812.04948/) (2018)
- [Generative Adversarial Networks](https://mlsanity.com/paper/2203.00667/) (2022)
- [You Only Look Once: Unified, Real-Time Object Detection](https://mlsanity.com/paper/1506.02640/) (2015)
- [Domain Randomization for Transferring Deep Neural Networks from Simulation to the Real World](https://mlsanity.com/paper/1703.06907/) (2017)
- [Class-Balanced Loss Based on Effective Number of Samples](https://mlsanity.com/paper/1901.05555/) (2019)
- [EfficientNetV2: Smaller Models and Faster Training](https://mlsanity.com/paper/2104.00298/) (2021)
- [DeCAF: A Deep Convolutional Activation Feature for Generic Visual Recognition](https://mlsanity.com/paper/1310.1531/) (2013)
- [Deep Long-Tailed Learning: A Survey](https://mlsanity.com/paper/2110.04596/) (2021)
- [A Comprehensive Survey on Data Augmentation](https://mlsanity.com/paper/2405.09591/) (2024)
- [A survey on learning from imbalanced data streams: taxonomy, challenges, empirical study, and reproducible experimental framework](https://mlsanity.com/paper/2204.03719/) (2022)
- [RoboCulture: A Robotics Platform for Automated Biological Experimentation](https://mlsanity.com/paper/2505.14941/) (2025)
- [Bubble identification from images with machine learning methods](https://mlsanity.com/paper/2202.03107/) (2022)
- [BubbleID: A Deep Learning Framework for Bubble Interface Dynamics Analysis](https://mlsanity.com/paper/2405.07994/) (2024)

## Abstract (arXiv)

Self-driving laboratories offer a promising path toward reducing the labor-intensive, time-consuming, and often irreproducible workflows in the biological sciences. Yet their stringent precision requirements demand highly robust models whose training relies on large amounts of annotated data. However, this kind of data is difficult to obtain in routine practice, especially negative samples. In this work, we focus on pipetting, the most critical and precision sensitive action in SDLs. To overcome the scarcity of training data, we build a hybrid pipeline that fuses real and virtual data generation. The real track adopts a human-in-the-loop scheme that couples automated acquisition with selective human verification to maximize accuracy with minimal effort. The virtual track augments the real data using reference-conditioned, prompt-guided image generation, which is further screened and validated for reliability. Together, these two tracks yield a class-balanced dataset that enables robust bubble detection training. On a held-out real test set, a model trained entirely on automatically acquired real images reaches 99.6% accuracy, and mixing real and generated data during training sustains 99.4% accuracy while reducing collection and review load. Our approach offers a scalable and cost-effective strategy for supplying visual feedback data to SDL workflows and provides a practical solution to data scarcity in rare event detection and broader vision tasks.