# Agentic Policy Optimization via Instruction-Policy Co-Evolution

arXiv: https://arxiv.org/abs/2512.01945 · HTML: https://mlsanity.com/paper/2512.01945/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Placed in Reinforcement learning for reasoning, one of 17 directions in LLM reasoning.
- Builds on 45 of its 78 references that are in the map.
- First posted on arXiv 1 Dec 2025.

## Placed in

- LLM reasoning / [Reinforcement learning for reasoning](https://mlsanity.com/lr/reinforcement-learning-for-reasoning/)
- LLM agents and tool use / [Reinforcement learning for LLM agents](https://mlsanity.com/agents/reinforcement-learning-for-llm-agents/)

## Builds on (most cited first, 30 of 45)

- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [Training language models to follow instructions with human feedback](https://mlsanity.com/paper/2203.02155/) (2022)
- [Proximal Policy Optimization Algorithms](https://mlsanity.com/paper/1707.06347/) (2017)
- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [DeepSeekMath: Pushing the Limits of Mathematical Reasoning in Open Language Models](https://mlsanity.com/paper/2402.03300/) (2024)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [ReAct: Synergizing Reasoning and Acting in Language Models](https://mlsanity.com/paper/2210.03629/) (2022)
- [Direct Preference Optimization: Your Language Model is Secretly a Reward Model](https://mlsanity.com/paper/2305.18290/) (2023)
- [Toolformer: Language Models Can Teach Themselves to Use Tools](https://mlsanity.com/paper/2302.04761/) (2023)
- [Dense Passage Retrieval for Open-Domain Question Answering](https://mlsanity.com/paper/2004.04906/) (2020)
- [Gemini 2.5: Pushing the Frontier with Advanced Reasoning, Multimodality, Long Context, and Next Generation Agentic Capabilities](https://mlsanity.com/paper/2507.06261/) (2025)
- [HotpotQA: A Dataset for Diverse, Explainable Multi-hop Question Answering](https://mlsanity.com/paper/1809.09600/) (2018)
- [SWE-bench: Can Language Models Resolve Real-World GitHub Issues?](https://mlsanity.com/paper/2310.06770/) (2023)
- [Scaling Instruction-Finetuned Language Models](https://mlsanity.com/paper/2210.11416/) (2022)
- [TriviaQA: A Large Scale Distantly Supervised Challenge Dataset for Reading Comprehension](https://mlsanity.com/paper/1705.03551/) (2017)
- [DAPO: An Open-Source LLM Reinforcement Learning System at Scale](https://mlsanity.com/paper/2503.14476/) (2025)
- [HybridFlow: A Flexible and Efficient RLHF Framework](https://mlsanity.com/paper/2409.19256/) (2024)
- [Search-R1: Training LLMs to Reason and Leverage Search Engines with Reinforcement Learning](https://mlsanity.com/paper/2503.09516/) (2025)
- [Understanding R1-Zero-Like Training: A Critical Perspective](https://mlsanity.com/paper/2503.20783/) (2025)
- [Constructing A Multi-hop QA Dataset for Comprehensive Evaluation of Reasoning Steps](https://mlsanity.com/paper/2011.01060/) (2020)
- [Text Embeddings by Weakly-Supervised Contrastive Pre-training](https://mlsanity.com/paper/2212.03533/) (2022)
- [When Not to Trust Language Models: Investigating Effectiveness of Parametric and Non-Parametric Memories](https://mlsanity.com/paper/2212.10511/) (2022)
- [Measuring and Narrowing the Compositionality Gap in Language Models](https://mlsanity.com/paper/2210.03350/) (2022)
- [Large Language Models Are Human-Level Prompt Engineers](https://mlsanity.com/paper/2211.01910/) (2022)
- [Interleaving Retrieval with Chain-of-Thought Reasoning for Knowledge-Intensive Multi-Step Questions](https://mlsanity.com/paper/2212.10509/) (2022)
- [MuSiQue: Multihop Questions via Single-hop Question Composition](https://mlsanity.com/paper/2108.00573/) (2021)
- [Large Language Models as Optimizers](https://mlsanity.com/paper/2309.03409/) (2023)
- [Automatic Prompt Optimization with "Gradient Descent" and Beam Search](https://mlsanity.com/paper/2305.03495/) (2023)
- [GEPA: Reflective Prompt Evolution Can Outperform Reinforcement Learning](https://mlsanity.com/paper/2507.19457/) (2025)
- [Search-o1: Agentic Search-Enhanced Large Reasoning Models](https://mlsanity.com/paper/2501.05366/) (2025)

## Built on by (most cited first, 3 of 3)

- [ReSkill: Reconciling Skill Creation with Policy Optimization in Agentic RL](https://mlsanity.com/paper/2606.01619/) (2026)
- [CAPO: Constraint-Aware Prompt Optimization for LLM Agents](https://mlsanity.com/paper/2608.16068/) (2026)
- [SkillScaffold: Scaffolding Agentic Reinforcement Learning with Policy-Adaptive Skill Credit Assignment and Selective Injection](https://mlsanity.com/paper/2610.18807/) (2026)

## Abstract (arXiv)

Reinforcement Learning with Verifiable Rewards (RLVR) has advanced the reasoning capability of large language models (LLMs), enabling autonomous agents that can conduct effective multi-turn and tool-integrated reasoning. While instructions serve as the primary protocol for defining agents, RLVR typically relies on static and manually designed instructions. However, those instructions may be suboptimal for the base model, and the optimal instruction may change as the agent's policy improves and explores the interaction with the environment. To bridge the gap, we introduce INSPO, a novel Instruction-Policy co-evolution framework that integrates instruction optimization as a dynamic component of the reinforcement learning (RL) loop. INSPO maintains a dynamic population of instruction candidates that are sampled with questions, where reward signals in RL loops are automatically attributed to each instruction, and low performers are periodically pruned. New instructions are generated and verified through an on-policy reflection mechanism, where an LLM-based optimizer analyzes past experience from a replay buffer and evolves more effective strategies given the current policy. We conduct extensive experiments on multi-turn retrieval and reasoning tasks, demonstrating that INSPO substantially outperforms strong baselines relying on static instructions. INSPO discovers innovative instructions that guide the agent toward more strategic reasoning paths, achieving substantial performance gains with only a marginal increase in computational overhead.