# Generalised Medical Phrase Grounding

arXiv: https://arxiv.org/abs/2512.01085 · HTML: https://mlsanity.com/paper/2512.01085/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 30 of its 40 references that are in the map.
- First posted on arXiv 30 Nov 2025.

## Builds on (most cited first, 30 of 30)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks](https://mlsanity.com/paper/1506.01497/) (2015)
- [End-to-End Object Detection with Transformers](https://mlsanity.com/paper/2005.12872/) (2020)
- [Visual Genome: Connecting Language and Vision Using Crowdsourced Dense Image Annotations](https://mlsanity.com/paper/1602.07332/) (2016)
- [Generalized Intersection over Union: A Metric and A Loss for Bounding Box Regression](https://mlsanity.com/paper/1902.09630/) (2019)
- [Modeling Context in Referring Expressions](https://mlsanity.com/paper/1608.00272/) (2016)
- [MDETR -- Modulated Detection for End-to-End Multi-Modal Understanding](https://mlsanity.com/paper/2104.12763/) (2021)
- [Making the Most of Text Semantics to Improve Biomedical Vision--Language Processing](https://mlsanity.com/paper/2204.09817/) (2022)
- [Learning to Exploit Temporal Structure for Biomedical Vision-Language Processing](https://mlsanity.com/paper/2301.04558/) (2023)
- [Exploring and Distilling Posterior and Prior Knowledge for Radiology Report Generation](https://mlsanity.com/paper/2106.06963/) (2021)
- [MAIRA-2: Grounded Radiology Report Generation](https://mlsanity.com/paper/2406.04449/) (2024)
- [Interactive and Explainable Region-guided Radiology Report Generation](https://mlsanity.com/paper/2304.08295/) (2023)
- [Improving Chest X-Ray Report Generation by Leveraging Warm Starting](https://mlsanity.com/paper/2201.09405/) (2022)
- [Chest ImaGenome Dataset for Clinical Reasoning](https://mlsanity.com/paper/2108.00316/) (2021)
- [Toward Visual Grounding: A Survey](https://mlsanity.com/paper/2412.20206/) (2024)
- [Multimodal Healthcare AI: Identifying and Designing Clinically Relevant Vision-Language Applications for Radiology](https://mlsanity.com/paper/2402.14252/) (2024)
- [GREC: Generalized Referring Expression Comprehension](https://mlsanity.com/paper/2308.16182/) (2023)
- [MedVersa: A Generalist Foundation Model for Medical Image Interpretation](https://mlsanity.com/paper/2405.07988/) (2024)
- [PadChest-GR: A Bilingual Chest X-ray Dataset for Grounded Radiology Report Generation](https://mlsanity.com/paper/2411.05085/) (2024)
- [Medical Phrase Grounding with Region-Phrase Context Contrastive Alignment](https://mlsanity.com/paper/2303.07618/) (2023)
- [VividMed: Vision Language Model with Versatile Visual Grounding for Medicine](https://mlsanity.com/paper/2410.12694/) (2024)
- [BioClinical ModernBERT: A State-of-the-Art Long-Context Encoder for Biomedical and Clinical NLP](https://mlsanity.com/paper/2506.10896/) (2025)
- [Longitudinal Data and a Semantic Similarity Reward for Chest X-Ray Report Generation](https://mlsanity.com/paper/2307.09758/) (2023)
- [ChEX: Interactive Localization and Region Description in Chest X-rays](https://mlsanity.com/paper/2404.15770/) (2024)
- [Visual Grounding of Whole Radiology Reports for 3D CT Images](https://mlsanity.com/paper/2312.04794/) (2023)
- [e-Health CSIRO at RRG24: Entropy-Augmented Self-Critical Sequence Training for Radiology Report Generation](https://mlsanity.com/paper/2408.03500/) (2024)
- [The Impact of Auxiliary Patient Data on Automated Chest X-Ray Report Generation and How to Incorporate It](https://mlsanity.com/paper/2406.13181/) (2024)
- [Zero-Shot Medical Phrase Grounding with Off-the-shelf Diffusion Models](https://mlsanity.com/paper/2404.12920/) (2024)
- [Anatomical grounding pre-training for medical phrase grounding](https://mlsanity.com/paper/2502.16585/) (2025)
- [Generate to Ground: Multimodal Text Conditioning Boosts Phrase Grounding in Medical Vision-Language Models](https://mlsanity.com/paper/2507.12236/) (2025)

## Built on by (most cited first, 1 of 1)

- [MedGround: Bridging the Evidence Gap in Medical Vision-Language Models with Verified Grounding Data](https://mlsanity.com/paper/2601.06847/) (2026)

## Abstract (arXiv)

Medical phrase grounding (MPG) maps textual descriptions of radiological findings to corresponding image regions. These grounded reports are easier to interpret, especially for non-experts. Existing MPG systems mostly follow the referring expression comprehension (REC) paradigm and return exactly one bounding box per phrase. Real reports often violate this assumption. They contain multi-region findings, non-diagnostic text, and non-groundable phrases, such as negations or descriptions of normal anatomy. Motivated by this, we reformulate the task as generalised medical phrase grounding (GMPG), where each sentence is mapped to zero, one, or multiple scored regions. To realise this formulation, we introduce the first GMPG model: MedGrounder. We adopted a two-stage training regime: pre-training on report sentence--anatomy box alignment datasets and fine-tuning on report sentence--human annotated box datasets. Experiments on PadChest-GR and MS-CXR show that MedGrounder achieves strong zero-shot transfer and outperforms REC-style and grounded report generation baselines on multi-region and non-groundable phrases, while using far fewer human box annotations. Finally, we show that MedGrounder can be composed with existing report generators to produce grounded reports without retraining the generator.