# OctoMed: Data Recipes for State-of-the-Art Multimodal Medical Reasoning

arXiv: https://arxiv.org/abs/2511.23269 · HTML: https://mlsanity.com/paper/2511.23269/

## Key facts

- Cited by 10 papers in the map (data through 14 Oct 2026).
- Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning.
- Builds on 53 of its 74 references that are in the map.
- First posted on arXiv 28 Nov 2025.

## Placed in

- LLM reasoning / [Clinical and biomedical applications](https://mlsanity.com/lr/clinical-and-biomedical-applications/)

## Builds on (most cited first, 30 of 53)

- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [DeepSeek-R1: Incentivizing Reasoning Capability in LLMs via Reinforcement Learning](https://mlsanity.com/paper/2501.12948/) (2025)
- [Efficient Memory Management for Large Language Model Serving with PagedAttention](https://mlsanity.com/paper/2309.06180/) (2023)
- [Qwen2.5-VL Technical Report](https://mlsanity.com/paper/2502.13923/) (2025)
- [GPT-4o System Card](https://mlsanity.com/paper/2410.21276/) (2024)
- [MMLU-Pro: A More Robust and Challenging Multi-Task Language Understanding Benchmark](https://mlsanity.com/paper/2406.01574/) (2024)
- [InternVL3.5: Advancing Open-Source Multimodal Models in Versatility, Reasoning, and Efficiency](https://mlsanity.com/paper/2508.18265/) (2025)
- [LlamaFactory: Unified Efficient Fine-Tuning of 100+ Language Models](https://mlsanity.com/paper/2403.13372/) (2024)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [s1: Simple test-time scaling](https://mlsanity.com/paper/2501.19393/) (2025)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [Does Reinforcement Learning Really Incentivize Reasoning Capacity in LLMs Beyond the Base Model?](https://mlsanity.com/paper/2504.13837/) (2025)
- [Vision-R1: Incentivizing Reasoning Capability in Multimodal Large Language Models](https://mlsanity.com/paper/2503.06749/) (2025)
- [MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answering](https://mlsanity.com/paper/2203.14371/) (2022)
- [MMMU-Pro: A More Robust Multi-discipline Multimodal Understanding Benchmark](https://mlsanity.com/paper/2409.02813/) (2024)
- [MAmmoTH: Building Math Generalist Models through Hybrid Instruction Tuning](https://mlsanity.com/paper/2309.05653/) (2023)
- [LLaVA-CoT: Let Vision Language Models Reason Step-by-Step](https://mlsanity.com/paper/2411.10440/) (2024)
- [MedGemma Technical Report](https://mlsanity.com/paper/2507.05201/) (2025)
- [Med-BERT: pre-trained contextualized embeddings on large-scale structured electronic health records for disease prediction](https://mlsanity.com/paper/2005.12833/) (2020)
- [R1-Onevision: Advancing Generalized Multimodal Reasoning through Cross-Modal Formalization](https://mlsanity.com/paper/2503.10615/) (2025)
- [PMC-VQA: Visual Instruction Tuning for Medical Visual Question Answering](https://mlsanity.com/paper/2305.10415/) (2023)
- [OpenThoughts: Data Recipes for Reasoning Models](https://mlsanity.com/paper/2506.04178/) (2025)
- [Lingshu: A Generalist Foundation Model for Unified Multimodal Medical Understanding and Reasoning](https://mlsanity.com/paper/2506.07044/) (2025)
- [MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understanding](https://mlsanity.com/paper/2501.18362/) (2025)
- [Spurious Rewards: Rethinking Training Signals in RLVR](https://mlsanity.com/paper/2506.10947/) (2025)
- [HuatuoGPT-Vision, Towards Injecting Medical Visual Knowledge into Multimodal LLMs at Scale](https://mlsanity.com/paper/2406.19280/) (2024)
- [RegMix: Data Mixture as Regression for Language Model Pre-training](https://mlsanity.com/paper/2407.01492/) (2024)
- [MedVLM-R1: Incentivizing Medical Reasoning Capability of Vision-Language Models (VLMs) via Reinforcement Learning](https://mlsanity.com/paper/2502.19634/) (2025)
- [MAIRA-2: Grounded Radiology Report Generation](https://mlsanity.com/paper/2406.04449/) (2024)

## Built on by (most cited first, 10 of 10)

- [ClinSeekAgent: Automating Multimodal Evidence Seeking for Agentic Clinical Reasoning](https://mlsanity.com/paper/2605.20176/) (2026)
- [When Does RL Help Medical VLMs? Disentangling Vision, SFT, and RL Gains](https://mlsanity.com/paper/2603.01301/) (2026)
- [MedAction: Towards Active Multi-turn Clinical Diagnostic LLMs](https://mlsanity.com/paper/2605.07305/) (2026)
- [MMBU: A Massive Multi-modal Biomedical Understanding Benchmark to Probe the Perception Capabilities of Vision-Language Models](https://mlsanity.com/paper/2606.06696/) (2026)
- [OpenMedReason: Scientific Reasoning Supervision for Medical Vision-Language Models](https://mlsanity.com/paper/2606.12169/) (2026)
- [MedGPT-oss: Training a General-Purpose Vision-Language Model for Biomedicine](https://mlsanity.com/paper/2603.00842/) (2026)
- [PathoSage: Towards Multi-Source Evidence Adjudication in Pathology via Experience-Aware Agentic Workflow](https://mlsanity.com/paper/2606.07549/) (2026)
- [DeepLens Diagnosis Agent: Agentic Workflow Design Lets a Small Reasoning Model Compete with Frontier LLMs](https://mlsanity.com/paper/2607.22555/) (2026)
- [PathScale-R1: Cross-scale Reasoning for Pathological Image Analysis](https://mlsanity.com/paper/2607.23794/) (2026)
- [Volumetric Radiology AI in the Era of Multimodal Large Language Models](https://mlsanity.com/paper/2608.20549/) (2026)

## Abstract (arXiv)

High-quality and carefully curated data is a cornerstone of training medical large language models, as it directly impacts both generalization and robustness to unseen clinical tasks. We investigate strategies for training and data curation to develop a robust multimodal reasoning model in the medical domain. Our work focuses on supervised fine-tuning (SFT) and explores data recipes that leverage structured reasoning traces. Using our proposed data recipe, we scale experiments to a dataset of over 8 million examples and 6.8 billion response tokens, achieving state-of-the-art performance among open-source models across diverse out-of-distribution medical benchmark tasks. Our results further indicate that curating a high-quality, diverse training dataset with varying structured reasoning trace lengths enables the fine-tuned model to self-calibrate its reasoning trajectory lengths based on the downstream task, without explicit supervision. We present key insights, describe the data curation strategy, and outline next steps toward developing robust medical vision-language reasoning system.